儿童术中七氟烷和地氟烷麻醉后苏醒期躁动情况比较

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Abstract Objective: To compare the emergence agitation in pediatric patients undergoing minor ENT surgery under sevoflurane or desflurane anesthesia. Methods: One hundred children of 1-7 years old undergoing minor ear-nose-throat (ENT) surgery were randomly divided into two groups: 50 cases in sevoflurane group (S group) and 50 cases in desflurane group (D group). After inhaled 8% sevoflurane combined 70% nitrous oxide with 10 L/min fresh gas, an IV was established and fentanyl 2 μg/kg followed by rocuronium 0.4 mg/kg was administered to facilitate endotracheal intubation. For maintenance of anesthesia, children were randomly assigned to receive either sevoflurane (1.0±0.2 ) MAC or desflurane (1.0±0.2) MAC, with a constant fresh gas flow of 2 L/minnute of 50% nitrous oxide in oxygen. The HR, MAP, SPO2 of admission to OR (T1), during the operation (T2), after extubation (T3) were recorded. Besides, degree of agitation using PAED scale, modified Aldrete scores and CHIPPS scores on admission to PACU were all recorded and followed every 10 minutes. Results: PAED scores in D group were significantly lower than S group at admission and 10 minnutes after PACU (P<0.01). Modified Aldrete scores in D group were also significantly higer than S group at admission and 10 minnutes in PACU (P<0.01, P<0.05). Besides, CHIPPS pain score in D group was significantly lower than S group when arriving in PACU (P<0.01). Conclusion: The emergence agitation associated with the use of desflurane is lower than sevoflurane anesthesia in children undergoing minor ENT surgery.

Key words： children surgery inhalation anesthesia anesthetic emergence agitation

Received: 02 February 2017

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	Articles by authors
	YE Xuefei
	HUANG Wenguang
	QIN Peishun
	LIN Han
	LIAN Qingquan.

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2018/V48/I2/131

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