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Diagnostic value of apparent diffusion coefficient in pelvic lymph nodes metastasis of cervical cancer |
DONG Ledan, XIAO Qinqin, XU Huazhi, YE Qiong. |
Department of Radiology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015 |
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Cite this article: |
DONG Ledan,XIAO Qinqin,XU Huazhi, et al. Diagnostic value of apparent diffusion coefficient in pelvic lymph nodes metastasis of cervical cancer[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2017, 47(11): 815-819.
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Abstract Objective: To study the diagnostic value of apparent diffusion coefficient in pelvic lymph nodes metastasis of cervical cancer. Methods: Thirty-six patients of cancer patients were selected from August 2015 to May 2017, who were examined with preoperative 3.0T MRI in the First Affiliated Hospital of Wenzhou Medical University. Total 169 cervical cancer pelvic lymph nodes were collected, of which 70 metastatic lymph nodes (metastatic group) and 99 non-metastatic lymph nodes (non-metastatic group). The difference of the ADC values, the longest diameter, the shortest diameter, the volume of lymph nodes and the short/long ratio of metastatic lymph nodes and non-metastatic lymph nodes were analyzed using Wilcoxon test. Results: There was no significant difference of ADC values of lymph node between metastatic group and non-metastatic group (P>0.05). The longest diameter, the shortest diameter, the volume of metastatic group were longer than non-metastatic group (Z=-7.94, -7.76, -6.82, P<0.001), and the short/long ratio of metastatic group was smaller than non-metastatic group (Z=-1.12, P<0.001). Conclusion: The ADC diagnostic value on the pelvic lymph nodes metastatic of cervical cancer is not significant. However, combined with DWI and T2WI images to measure the size of lymph nodes can improve the diagnostic accuracy of metastatic lymph nodes.
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Received: 10 June 2017
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[1] TORRE L A, BRAY F, SIEGEL R L, et al. Global cancer statistics, 2012[J] CA Cancer J Clin, 2015, 65(2): 87-108.
[2] PECORELLI S. Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium[J]. Int J Gynaecol Obstet, 2009, 105(2): 103-104.
[3] LIU Y, LIU H, BAI X, et al. Differentiation of metastatic from non-metastatic lymph nodes in patients with uterine cervical cancer using diffusion-weighted imaging[J]. Gynecol Oncol, 2011, 122(1): 19-24.
[4] ROY C, BIERRY G, MATAU A, et al. Value of diffusion-weighted imaging to detect small malignant pelvic lymph nodes at 3 T[J]. Eur Radiol, 2010, 20(8): 1803-1811.
[5] 陈慧君, 黄亦波, 林蓉蓉, 等. IB~IIB期宫颈癌盆腔淋巴结转移相关因素分析[J]. 温州医科大学学报, 2015, 45(4): 248-251.
[6] SCHOB S, MEYER H J, PAZAITIS N, et al. ADC histogram analysis of cervical cancer aids detecting lymphatic metastases-a preliminary study[J]. Mol Imaging Biol, 2017, 19(6): 953-962.
[7] RECHICHI G, GALIMBERTI S, ORIANI M, et al. ADC maps in the prediction of pelvic lymph nodal metastatic regions in endometrial cancer[J]. Eur Radiol, 2013, 23(1): 65-74.
[8] KUANG F, REN J, ZHONG Q, et al. The value of apparent diffusion coefficient in the assessment of cervical cancer[J]. Eur Radiol, 2013, 23(4): 1050-1058.
[9] WANG Y T, LI Y C, YIN L L, et al. Can diffusion-weighted magnetic resonance imaging predict survival in patients with cervical cancer? A meta-analysis[J]. Eur J Radiol, 2016, 85(12): 2174-2181.
[10] GIANNARINI G, PETRALIA G, THOENY H C. Potential and limitations of diffusion-weighted magnetic resonance imaging in kidney, prostate, and bladder cancer including pelvic lymph node staging: a critical analysis of the litera-ture[J]. Eur Urol, 2012, 61(2): 326-340.
[11] MACDONALD O K, CHEN J, DODSON M, et al. Prognostic significance of histology and positive lymph node involvement following radical hysterectomy in carcinoma of the cervix[J]. Am J Clin Oncol, 2009, 32(4): 411-416.
[12] WU X, REINIKAINEN P, KAPANEN M, et al. Diffusion-weighted MRI provides a useful biomarker for evaluation of radiotherapy efficacy in patients with prostate cancer[J]. Anticancer Res, 2017, 37(9): 5027-5032.
[13] PAPALIA R, SIMONE G, GRASSO R, et al. Diffusion-weighted magnetic resonance imaging in patients selected for radical cystectomy: detection rate of pelvic lymph node metastases[J]. BJU Int, 2012, 109(7): 1031-1036.
[14] EIBER M, BEER A J, HOLZAPFEL K, et al. Preliminary results for characterization of pelvic lymph nodes in patients with prostate cancer by diffusion-weighted MR-imaging[J]. Invest Radiol, 2010, 45(1): 15-23.
[15] VANDECAVEYE V, DE KEYZER F, VANDER P V, et al. Head and neck squamous cell carcinoma: value of diffusion-weighted MR imaging for nodal staging[J]. Radiology, 2009, 251(1): 134-146.
[16] THOENY H C, FROEHLICH J M, TRIANTAFYLLOU M, et al. Metastases in normal-sized pelvic lymph nodes: detection with diffusion-weighted MR imaging[J]. Radiology, 2014, 273(1): 125-135.
[17] SCHOB S, MEYER H J, DIECKOW J, et al. Histogram analysis of diffusion weighted imaging at 3T is useful for prediction of lymphatic metastatic spread, proliferative activity, and cellularity in thyroid cancer[J]. Int J Mol Sci, 2017, 18(4): E821.
[18] RABASCO P, CAIVANO R, SIMEON V, et al. Can diffusion-weighted imaging and related apparent diffusion coefficient be a prognostic value in women with breast can-cer?[J]. Cancer Invest, 2017, 35(2): 92-99.
[19] NAKAI G, MATSUKI M, INADA Y, et al. Detection and evaluation of pelvic lymph nodes in patients with gynecologic malignancies using body diffusion-weighted magnetic resonance imaging[J]. J Comput Assist Tomogr, 2008, 32(5): 764-768.
[20] CHEN Y B, LIAO J, XIE R, et al. Discrimination of metastatic from hyperplastic pelvic lymph nodes in patients with cervical cancer by diffusion-weighted magnetic resonance imaging[J]. Abdom Imaging, 2011, 36(1): 102-109.
[21] WU Q, ZHENG D, SHI L, et al. Differentiating metastatic from nonmetastatic lymph nodes in cervical cancer patients using monoexponential, biexponential, and stretched exponential diffusion-weighted MR imaging[J]. Eur Radiol, 2017.
[22] 贺李, 余深平, 庄晓曌, 等. 3.0T磁共振DWIBS诊断宫颈癌转移性淋巴结初探[J]. 影像诊断与介入放射学, 2010, 19 (5): 273-276. |
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