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Abstract Objective: To explore the changes of routine blood and coagulation tests in 203 high-risk pregnancy patients. Methods: The results were based on a retrospective analysis of 203 high-risk pregnancy cases in the First Affiliated Hospital of Wenzhou Medical University from 2015.1 to 2016.3. Routine blood and coagulation tests were detected by Sysmex XE-2100 and STAGO analyzer respectively. 203 high-risk pregnancy cases were divided into three groups: mild group (62 cases), medium group (76 cases) and severe group (65 cases). Compare the results with 46 normal pregnancy patients and 51 non-pregnant cases. Results: It showed a remarkable decline in HGB, Hct, PLT of all pregnancy groups compared with non-pregnant women, whereas significant increase was in RDW (P<0.01). There’re no significant difference in MCV between all groups (P>0.05). Compared with non-pregnant women, PT, APTT, TT showed a remarkable decline in all pregnancy groups except severe group (P<0.05 or P<0.01). Fibrinogen (FIB) and D-D showed significant increase over non-pregnant women (P<0.01). And PT, APTT, TT, D-D in severe group showed significant increase over the other pregnancy groups (P<0.01), FIB showed the exact contrary (P<0.01). Conclusion: There’re more obvious changes of routine blood and coagulation tests in pregnancy cases especially in severe group. Routine blood and coagulation tests were very important for high-risk pregnancy patients

Received: 11 July 2016

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	XU Fei
	XU Xiaojie
	LI Xiaolong
	YANG Lihong
	LIU Huanle
	JIANG Ye
	WANG Mingshan

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2017/V47/I7/530