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The expression change of sarcoglycan in the detrusor muscle of unstable bladder caused by benign prostatic hyperplasia |
MU Haiqi1, ZHU Shijian2, WANG Shuaibin1, NAN Cunjin1, BAO Yunfan1, CHEN Yinghe1. |
1.Department of Urology, the Second Affiliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, 325027; 2.Department of Urology, Cangnan Hospital Affiliated to Wenzhou Medical University, Wenzhou, 325800
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Cite this article: |
MU Haiqi,ZHU Shijian,WANG Shuaibin, et al. The expression change of sarcoglycan in the detrusor muscle of unstable bladder caused by benign prostatic hyperplasia[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2017, 47(5): 366-368.
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Abstract Objective: To study the expression change of sarcoglycan (SG) in the detrusor muscle of the unstable bladder caused by benign prostatic hyperplasia (BPH). Methods: 34 cases of stable bladder and 26 cases of unstable bladder were included in this study. The expressions of α-SG, β-SG, γ-SG in detrusor muscle of bladder were detected by immunohistochemical technique Western-blot and RT-PCR. Results: Compared to the group of stable bladder, the expression of SG in detrusor muscle of unstable bladder caused by BPH was increased (P<0.05). Conclusion: The changes of SG in the detrusor muscle of bladder may closely related to the production of unstable bladder caused by BPH.
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Received: 13 June 2016
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