超声造影在细胞学不能明确诊断的甲状腺结节中的应用

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Abstract Objective: To evaluate the diagnostic value of the contrast enhanced ultrasound (CEUS) in the thyroid nodule less than 0.5 cm with an initial inconclusive diagnostic fine needle aspiration cytology (FNA).Methods: A retrospective analysis of the clinical data of 61 patients was performed, including 63 thyroid nodules with L<0.5 cm. All the thyroid nodules had an initial inconclusive diagnostic FNA and undergone CEUS, a repeat FNA after 3 months and finally confirmed by pathology. All the imaging data of preoperative FNAs and CEUS were collected. Pursuant to which, the detection rate of malignant nodules (DROMN), the detection rate of begin nodules (DROBN), the false negative rate (FNR), the false positive rate (FPR), the accuracy of diagnosis, the persistently inconclusive diagnostic rate (PIDR) and the malignant proportion by repeat FNA and CEUS were analyzed respectively. Results: In CEUS group, the DROMN, DROBN, FNR, FPR, the accuracy of diagnosis, PIDR and the malignant rate were 84.8%, 36.7%, 15.3%, 12.5%, 86.7%, 28.5% and 16.7% respectively. In the repeat FNA group, DROMN, DROBN, FNR, FPR, the accuracy of diagnosis, PIDR and the malignant proportion were 24.2%, 33.3%, 41.2%, 0.0%, 72.0%, 60.3%, 47.4%. The DROMN, PIDR and the malignant rate in the group CEUS were statistically higher than the repeat FNA group (P<0.05). Conclusion: CEUS has a better diagnostic efficiency in the thyroid nodule less than 0.5 cm with an initial inconclusive diagnostic FNA than the repeat FNA. The non-invasive CEUS examination can be suggested.

Key words： ultrasonography thyroid nodule contrast enhanced ultrasound fine needle aspiration cytology

Received: 17 March 2016

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	CHEN Jianshe
	ZHANG Chao
	LUO Jieli
	SUN Yang
	HUANG Pintong.

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2017/V47/I2/128

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