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| The analysis of cerebral vasospasm risk factor after aneurysms subarachnoid hemorrhage |
Department of Neurosurgery, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027
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LIN Zhongxiao,JIN Qianqian,YOU Chaoguo, et al. The analysis of cerebral vasospasm risk factor after aneurysms subarachnoid hemorrhage[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(8): 575-577,581.
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Abstract Objective: To analyze the occurrence and risk factor of cerebral vasospasm (CVS) after aneurysms subarachnoid hemorrhage (aSAH). It was useful to provid theoretical basis for the treatment and preventation of the CVS. Methods: The clinical data of 115 patients were retrospectively analyzed. The Chi-squared test and logistic multivariate analysis were used to analyze and assess cerebral vasospasm rate and high-risk factors. Results: The Chi-squared test showed that 52 patients appeared the CVS, and the occurrence rate of the CVS was 45.21% in 115 patients. Hunt grades, improved modified FISH grades, therapy methods and nimodpine were related to the CVS (P<0.05). But age, gender, history of hypertension, history of smoking, serous potassium, blood glucose and white blood cell were irrelated to the CVS (P>0.05). Multivariate logistic analysis revealed that therapy methods were irrelated to the CVS (P>0.05). However, Hunt grades, improved modified FISH grades (b>0, OR>1) were independent risk factor of the CVS (P<0.05), and nimodpine was a protective factor (b<0, OR<1) of the CVS (P<0.05). Conclusion: aSAH patients are vulnerable to the CVS. Nimodipine is a protective factor of the CVS, however, Hunt grades and improved modified FISH grades are high risk factors of the CVS.
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Received: 22 September 2015
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