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| Relationship between heart rate turbulence changes and parathyroid hormone in uremic patients |
| WANG Yongye, LI Ruofu |
Department of Nephrology, the People’s Hospital of Cangnan, Wenzhou, 325800
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| Cite this article: |
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WANG Yongye,LI Ruofu.. Relationship between heart rate turbulence changes and parathyroid hormone in uremic patients[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(6): 461-463.
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Abstract Objective: To discuss the relationship between heart rate turbulence (HRT) changes and parathyroid hormone in uremic patients. Methods: Eighty-two MHD patients were divided into group A (iPTH>300 ng/L) and group B (iPTH≤300 ng/L) according parathyroid hormone levels. The patients of group A were given treatment of hemodialysis, blood phosphorus reduction and calcitriol, group B were only given treatment of hemodialysis. All patients underwent 24 h ambulatory electrocardiogram, the turbulence onset (TO) and turbulence slope (TS) were calculated. Blood creatinine, parathyroid hormone were observed before and after treatment. Results: Compared with group B, TO was increased (P<0.05), but TS decreased significantly in group A (P<0.05). Parathyroid hormone levels were positively correlated with TO (r=0.435, P<0.05), and were negatively correlated with TS (r=-0.238, P<0.05). Conclusion: Heart rate turbulence is significantly impaired in uremic patients. Secondary hyperparathyroidism (SHPT) is closely related to HRT. Treatment of SHPT is helpful to HRT.
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Received: 10 March 2015
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. [J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2022, 52(7): 595-597. |
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