降钙素原在慢性阻塞性肺疾病急性加重期指导抗生素使用的价值

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Abstract Objective: To investigate the value of procalcitonin (PCT) in guiding antibiotic therapy for acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods: Totally 134 patients with AECOPD were randomly divided into PCT group (47 cases), Guide group (42 cases) and Experience group (45 cases). Three groups of clinical efficacy, the total medical costs, costs of antibiotic therapy and hospitalization days were statistically analysed. Results: Between the PCT group and the guide group in the total medical costs, costs of antibiotics and hospitalization days had no statistically significant difference (P>0.05). PCT group and guide group in the total medical costs, costs of antibiotics and hospitalization days were statistically significant difference compared with the experience group (P<0.05). There was no significant diference in cases of clinical efficacy among the three groups (P>0.05). Conclusion: PCT detection can effectively reduce the total costs of hospitalization, which can also reduce costs of antibiotic therapy and the duration of hospital stay in the treatment of AECOPD patients.

Key words： procalcitonin chronic obstructive pulmonary disease acute exacerbation antibiotic therapy

Received: 12 November 2015

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	WU Tianxian
	JIN Xuewen
	ZHANG Yehui
	HUANG Juhong
	ZHENG Yulin.

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2016/V46/I4/292

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