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| Effects of heterologous acellular dermal matrix combined with autologous skin grafts on the residual wounds with titanium mesh in skull defects |
| LUO Xu1, LIN Cai1, WANG Xinling2. |
1.Department of Wounds and Burns Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015; 2.Department of Outpatient Services Center, the Taihe Hospital of Hubei Medical College, Shiyan, 442000
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| Cite this article: |
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LUO Xu,LIN Cai,WANG Xinling.. Effects of heterologous acellular dermal matrix combined with autologous skin grafts on the residual wounds with titanium mesh in skull defects[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(4): 287-288.
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Abstract Objective: To explore the therapeutic means of heterologous acellular dermal matrix (ADM) combined with autologous skin graft (ASG) to repair the residual skull defective wounds with titanium mesh exposed. Methods: Heterologous acellular dermal matrix (phase I) combined with autologous skin graft (phase II) transplantation operation was used in 10 patients of titanium mesh skull defect with exposed residual wound. The wound heal situation was observed. Results: ADM and ASG were all alive in 10 patients. Healing of type II incision on the wound was in grade I. The average operation duration was 30-45 min, while the average volume of blood loss was 30-50 mL. After follow-up observation for three months, skin elasticity at the surgical transplantation area was good without damage. Conclusion: The new therapeutic method for repairing the residual wound with exposure titanium mesh by means of ADM combined with ASG transplantation can avoid to some extent requiring more working time than other operations, such as regional perforating branch flap and free flap transplantation, and needn’t special equipment, adequate train and the complex preoperative preparation.
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Received: 02 July 2015
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[1] 张曙光, 潘天鸿, 周金方. 颞肌外钛网修补额颞区颅骨缺损[J]. 临床神经外科杂志, 2007, 4(1): 43-45.
[2] 王新功, 张健, 李冰. 不同颅骨修补材料术后并发症的防治策略[J]. 中国伤残医学, 2008, 16(2): 45-46.
[3] 季庆, 李佳, 郝继山, 等. 计算机辅助设计的个体化塑形钛网用于颅骨修补的临床研究[J]. 中华创伤杂志, 2007, 23(4): 250-252.
[4] 陈治强, 董伟, 张雷, 等. 颅骨修补用钛网与有机玻璃的临床比较[J]. 重庆医学, 2004, 33(11): 3.
[5] 林才, 罗旭, 王平, 等. 激光微孔猪脱细胞真皮基质的制备及生物相容性评价[J]. 中华烧伤杂志, 2011, 27(6): 432-435.
[6] 罗旭, 辛国华, 曾逃方, 等. 微孔化猪脱细胞真皮基质与大鼠骨髓间充质细胞对裸鼠皮肤附件细胞再生的作用[J]. 中华烧伤杂志, 2013, 29(6): 541-547.
[7] 万丽, 罗旭, 辛国华, 等. 骨髓间充质干细胞接种微孔化脱细胞真皮基质复合自体刃厚皮移植修复裸鼠皮肤缺损的 实验研究[J]. 温州医学院学报, 2013, 43(3): 148-150. |
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