|
|
|
| The effect of intrauterine growth on mental and psychomoter development in one-year-old discordant twins infants |
| XIANG Huiqiu1, HUANG Xianping1, JIN Jiaxi1, SHAO Haoran2, CHI Meizhu2, LIN Feng3, XU Zhangye1. |
1.Department of Obstetrics, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027; 2.Department of Pediatrics, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015; 3.Department of Obstetrics, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015
|
|
| Cite this article: |
|
XIANG Huiqiu,HUANG Xianping,JIN Jiaxi, et al. The effect of intrauterine growth on mental and psychomoter development in one-year-old discordant twins infants[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(2): 84-87.
|
|
|
Abstract Objective: To assess the effect of intrauterine growth on mental and psychomoter development in one-year-old discordant twins infants. Methods: Total of 34 discordant twin pregnancies (68 one-year-old discordant twins infants) with complete delivery records in Obstetrics department of the First and Second Affiliated Hospital of Wenzhou Medical University from January 2012 to December 2013 were followed-up. According to the discordant birthweight, each pair infant was divided into small weight group and large weight group. Weight, length, head circumferences, the mental developmental index (MDI) and psychomotor developmental index (PDI) were measured. Results: Small weight group was lower than that of large group at length, weight and head circumstance (P<0.05); PDI but not MDI was significantly different between two groups (P<0.05). Psychomotor retardation rates (PDI<70) were 17.6% in small weight group while 2.9% in large weight group (P<0.05). Stepwise regression analysis showed that the influence of height and weight of PDI had significant statistical significance (P<0.05). Conclusion: Intrauterine fetal growth and development leads to twins after birth weight differences, and sustained impact to born after 1 year old children’s height, weight and head circumference of physical growth and psychomotor development.
|
|
Received: 10 September 2015
|
| |
|
|
|
[1] BREATHNACH F M, MCAULIFFE F M, GEARY M, et al. Definition of intertwin birth weight discordance[J]. Obstet Gynecol, 2011, 118(1): 94-103
[2] 王马列, 梁润彩. 发育不一致性双胎的研究进展[J]. 中华儿科杂志, 2011, 42(2): 135-138.
[3] SULLIVAN S A, NEWMAN R. Prediction and prevention of preterm delivery in multiple gestations[J]. Clin Obstet Gynecol, 2004, 47(1): 203-215.
[4] 王佳蓉. 双胎胎儿生长不一致妊娠结局的探讨分析[J]. 中国实用医药, 2014, 9(15): 47-48.
[5] BLICKSTEIN I, KEITH L G. Neonatal mortality rates among growth-discordant twins, classified according to the birth weight of the smaller twin[J]. Am J Obstet Gynecol, 2004, 190(1): 170-174.
[6] ADEGBITE A L, CASTILLE S, WARD S, et al. Neuromorbidity in pteterm twins in relation to chorionicity and discordant birth weight[J]. Am J Obstet Gynecol, 2004, 190(1): 156-163.
[7] EDMONDS C J, ISSAACS E B, COLE T J, et.al. The effect of intrauterine growth on Verbal IQ scores in childhood: A study of monozygotic twins[J]. Pediatrics，2010, 126(5): 1095-1101.
[8] 朱正方, 许开贵, 张莲玉, 等. 双胎儿童智能发育的影响因素及预防[J]. 中国优生与遗传杂志. 2004, 12(6): 103-112.
[9] LUCIANO M, WRIGHT M J, MARTIN N G. Exploring the etiology of the association between birthweight and IQ in an adolescent twin sample[J]. Twin Res, 2004, 7(1): 62-71.
|
|
|
|
