中西医结合治疗由喉咽反流导致的咽喉炎疗效分析

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Abstract Objective: To investigate the effect of Chinese traditional combined with Western medicine in treatment of pharyngitis caused by laryngopharyngeal reflux. Methods: Retrospectively analysis of treatment for throat discomfort, reflux symptom index (RSI) score >13 points and (or) reflux finding score (RFS) >7 points were positive, of which the score of RSF positive was 100 cases, the score of RSI positive 105 cases, combined with laryngoscope examination and clinical manifestations, 105 cases were diagnosed as LPR. 105 cases were Randomly divided into three groups. the treatment method included avoiding high fat, high sugar, hot and spicy diet and changing lifestyle (such as smoking, alcohol and no longer eat after 9 pm). 35 cases in A group were treated with omeprazole [proton pump inhibitor (PPI)], domperidone and jingshen moisten throat agent therapy, 35 cases of B group were treated with omeprazole and domperidone therapy, 35 cases of C group were treated with omeprazole therapy. The curative effect was observed after the end of treatment for 3 months. Results: In group A, 25 cases (71.43%) were markedly effective, 7 cases (20%) were effective, 3 cases (8.57%) were invalid, the total effective rate was 91.43%; in group B, 17 cases (48.57%) were markedly effective, 5 cases (14.29%) were effective, 13 cases (37.14%) were invalid, the total effective rate was 62.86%; in group C, 12 cases (34.29%) were markedly effective, 6 cases (17.14%) were effective, 17 cases (48.57%) were invalid, the total effective rate was 51.43%. The difference was statistically significant (x2=13.788, P<0.05) when comparison of the total efficiency among the three groups. Comparison between the two groups: the total effective rate of A group was higher than that of B group, and the difference was statistically significant (x2=6.563, P<0.0125), the total effective rate of A group was higher than that of C group, and the difference was statistically significant (x2=11.830, P<0.0125). The total effective rate between B group and C group were no significant difference, and the difference had no statistically significant (x2=0.933, P>0.0125). Main symptom remission time (weeks) in throat department in the A group was shorter than that in the B group, also shorter than that in the C group, main symptom remission time in the B group in throat department was shorter than that in the C group, the differences were statistically significant (all P<0.05). Conclusion: Traditional Chinese combined with Western medicine had better clinical effect in the treatment of pharyngitis caused by LPR.

Received: 27 February 2013

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	WU Xianmin1
	SHANGGUAN Hanjing2
	CHEN Xiaoyun1
	ZHANG Yue1
	LI He1
	CHEN Jianfu1

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2014/V44/I1/51

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