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| Comparison of the pregnancy outcomes of frozen blastocyst transferred 4 hours after being thawed or 20 hours after being cultured overnight |
Department of Reproductive Center, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027
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XI Haitao,GE Hongshan,CHI Haihong, et al. Comparison of the pregnancy outcomes of frozen blastocyst transferred 4 hours after being thawed or 20 hours after being cultured overnight[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2015, 45(10 ): 762-.
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Abstract Objective: To compare the pregnancy outcomes when frozen blastocyst was transferred 4 hours after being thawed or 20 hours after being cultured overnight. Methods: For the 5 days freezing thawing blastocysts transplantation cycle, all the cycles are divided into two groups based on different culture time before transfer, those blastocysts transferred 4 hours after being thawed were labeled as A group (n=157) and those cultured overnight before being transferred the next day were included in B group (n=227). The pregnancy outcomes were compared between the two groups. Results: The proportion of thawing cycles leading to no transfer did not differ between groups (1.2% versus 2.2% for A and B, respectively). However, the proportion of hatched blastocysts derived from B group was significantly higher than that from A group (41.7% versus 86.5%, respectively, P<0.001). All differences of the clinical pregnancy rate, implantation rate, miscarriage rate and multiple pregnancy rate between two groups have not yet reached the statistical significance. Conclusion: Overnight culture of thawed blastocyst before transfer does not affect the main pregnancy outcomes. For blastocyst thawing time, operators will have more choices.
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Received: 18 November 2014
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