促甲状腺激素水平与妊娠期代谢综合征的相关性分析

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Abstract Objective: To investigate the relationship between thyroid-stimulating hormone (TSH) levels and metabolic syndrome during pregnancy. Methods: Nine hundred and eleven single pregnant women who accepted regular obstetrical inspection and delivered in Wenzhou People’s Hospital were enrolled. One hundred and forty-nine cases with subclinical hypothyroidism (TSH>3.0 mIU/L) were divided into study group and other 762 pregnant women with TSH<3.0 mIU/L were as controls. Information Including age, gestational weeks, body weight before pregnancy and biochemical indicators, including total cholesterol (CHOL), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and thyroid-stimulating hormone levels were recorded. The levels of serum lipid, the prevalence of pregnancy induced hypertension, gestational diabetes mellitus and pregnancy metabolic syndrome were compared between the two group. Results: The levels of triglyceride in the subclinical hypothyroidism group were much higher than that in the controls. The difference was statistically significant (P<0.05). The incidence of GMS and pregnancy induced hypertension was much higher than that in the controls. There was no correlation between TSH and GMS (P>0.05). The TSH seemed to have relationship in the morbidity between pregnancy induced hypertension and normal (P<0.05). Conclusion: There is a significant correlation between TSH levels and triglyceride and pregnancy induced hypertension.The levels of TSH is also associated with pregnancy hypertension, but not related to GMS.

Key words： thyroid-stimulating hormone subclinical hypothyroidism gestational metabolic syndrome pregnancy induced hypertension

Received: 24 April 2015

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	ZHOU Qingdiao1
	ZHENG Xiaodong1
	LI Xiumei1
	HU Yanjun1
	LV Jieqiang2.

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2015/V45/I10 /758

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