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| Contrastive analysis between depression with chief complaint of xerostomia and Sjögren’s syndrome |
Department of Rheumatology, the People’s Hospital of Lishui, Lishui, 323000
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WANG Xiaodong,CHEN Jian,LIU Jian, et al. Contrastive analysis between depression with chief complaint of xerostomia and Sjögren’s syndrome[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2015, 45(10 ): 728-.
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Abstract Objective: To investigate the difference between depression with chief complaint of xerostomia and Sjögren’s syndrome (SS) by analyzing the clinical characteristics. Methods: The peripheral blood white cells, neutrophilic granulocytes, lymphocytes, CRP, immune globulin (Ig), auto antibodies, labial salivary gland biopsy, and parotid gland ECT in depression with chief complaint of xerostomia group, SS group, SS complicated with depression group and healthy people were evaluated respectively. Statistical analysis was used to find the difference between each group. Results: The peripheral blood white cells was lower in the depression group than that in the healthy control group (P<0.01), and the depression play a main effect on peripheral blood white cells. The CRP was higher in the depression group than the healthy control group (P<0.01), while there was no significant difference between the other two groups. The IgG level was the lowest in the four groups (P<0.05). The IgA and IgM level was higher in SS group and SS with depression group (P<0.01). SS played a main effect on increasing IgM and IgA. Although the positive rate of RF was lower in the depression group than that in SS and SS with depression group, there was no significant difference. The pathdogical examination did not find of small labial positive in the depression and healthy control group. Conclusion: In patients with the chief complaint of xerostomia with depression humoral immune abnormalities and acute inflammation also exists. These patients may be misdiagnosed as SS, if necessary, we must do small labial gland biopsy to be identified.
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Received: 15 December 2014
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[1] 房丽华, 赵岩, 曾小峰. 儿童原发性干燥综合征的临床特点[J]. 中华儿科杂志, 2004, 42(8): 568-570.
[2] 俞可佳, 袁风红, 胡赟霞, 等. 涎腺核素动态显像诊断干燥 综合征的临床研究[J]. 中华风湿病学杂志, 2011, 15(6):425-429.
[3] Chisholm DM, Mason DK. Labial salivary gland biopsy in Sjögren’s disease[J]. J Clini Path, 1968, 21(5): 656-660.
[4] Friedlander AH, Norman DC. Late-life depression: psychopathology, medical interventions,and dental implications[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2002, 94(4): 404-412.
[5] 韩彦超, 宗艳红, 张彦恒, 等. 117例抑郁症患者的躯体症状和首诊情况调查[J]. 中国心理卫生杂志, 2008, 22(12):874-877.
[6] 祖蓓蓓. 抑郁症与免疫抑制[J]. 国外医学精神病学分册, 2004, 31(2): 97-99.
[7] 杨兴洁, 施旺红, 杨业兵. 自身免疫病伴抑郁障碍的研究进展[J]. 中国行为医学科学, 2006, 15(10): 952-953.
[8] 郭珊, 郭克锋. 抑郁症的研究进展[J]. 中国临床康复, 2005,9(4): 131-133.
[9] 唐亚, 周利君, 刘勇, 等. 抑郁症患者血清CRP、CER、Hcy和Anti-CCP抗体的浓度变化[J]. 实用预防医学, 2012, 19 (9): 1399-1401.
[10] 杜爱玲, 王长虹, 杨世昌. 抑郁症的免疫学研究及心理治疗[J]. 神经疾病与精神卫生, 2007, 7(3): 230-232.
[11] 程敏锋, 温盛霖, 王厚亮. 抑郁症患者体液免疫的变化及临床意义[J]. 中国医师杂志, 2012, 12(11): 1546-1547.
[12] 陈勇, 黄小燕. 干燥综合征发病机制研究进展[J]. 现代预防医学, 2011, 38(20): 4328-4329.
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. [J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2021, 51(1): 70-71,74. |
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