B超联合细针穿刺细胞病理学在评价甲状腺结节中的应用

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Abstract Objective: To explore the application of ultrasonography combined with fine-needle aspiration (FNA) cytopathology on evaluating thyroid nodules. Methods: A total of 2 491 cases of thyroid surgery, of whom 249 cases were malignant from 2010 February to 2014 July were analyzed retrospectively, including the characteristics of ultrasonography and FNA cytopatholgoy. The former consisted of thyroid’s volume, number, size, hypoechogenecity, blur margin, microcalcification and taller-than-wide shape of thyroid nodule, the later included nuclear grooves, pseudoinclusions, ground glass and papillary architecture. Results: The single marker in thyroid ultrasonography related with malignancy was nodular microcalcification, single nodule larger than 2 cm and taller-than-wide nodule (all P<0.05), but all of which couldn’t tell the nature of thyroid nodules. The diagnostic sensitivity and specificity of FNA cytopathology on thyroid cancer was 88% and 77%, and the combination of ultrasonography and FNA cytopathology was 71% and 96%. Conclusion: In this regard of distinguishing the difference of benign and malignant nodule of thyroid, ultrasonography combined with FNA cytopathology is the first line and cost-effective evaluation method.

Key words： thyroid neoplasms ultrasonography, doppler biopsy, needle cytopatholgoy

Received: 15 January 2015

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	GONG Wei1
	FANG Weijian1
	CHEN Guorong2
	FENG Yaqin1

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2015/V45/I9/690

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