呼气峰流量日变异率及哮喘控制测试评分在哮喘病情监测中的作用

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Abstract Objective: To explore the value of application of diurnal peak expiratory flow variability and asthma control test (ACT) in monitoring patients with bronchial asthma. Methods: Sixty-four asthmatic patients were collected from section for outpatients of the Second Affiliated Hospital of Wenzhou Medical University dating from July 2013 to December 2013. Their peak expiratory flow readings were determined with four times a day (6:00, 12:00, 18:00, 24:00). The diurnal peak expiratory flow variability and the average individually were calculated, at the same time the ACT and the first breath rate of expected percentage (FEV1%) were recorded. Results: Diurnal peak expiratory flow variability showed no relationship with FEV1% and ACT scores, but ACT had positive correlation with FEV1% (r=0.658, P<0.05), the linear regression relationship was Y=49.79+1.48X. The area under the curve in receiver operator characteristic curve of diurnal peak expiratory flow variaility was 0.976 (cutoff point 0.2, sensitivity 100% and specificity 85.4%). The area under the curve in receiver operator characteristic curve of ACT was 0.771 (cutoff point 20, sensitivity 65.2% and specificity 64.6%). The area under the curve in receiver operator characteristic curve of diurnal peak expiratory flow variability together with ACT was 0.767 (sensitivity 45%, specificity 100%). ACT of patients with poorly controlled showed no correlation with diurnal peak expiratory flow variability, but in patients with well controlled, the ACT scores and diurnal peak expiratory flow variability had negative correlation (r=-0.602, P<0.01). Conclusion: ACT score can be used to speculate asthma patients’ FEV1% lung function index. Diurnal peak expiratory flow variability and ACT can be used in monitoring asthmaseparatly,so can they used together. In patients with asthma better controlled, doctoers can separate peak expiratory flowvariation rate by ACT score.

Key words： asthma diurnal peak expiratory flow variability asthma control test

Received: 23 September 2014

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	JIN Lingling
	LIN Hui
	DAI Yuanrong.

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2015/V45/I8/579

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