320排动态容积CT评估钙化斑块对诊断冠状动脉狭窄程度的影响

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Abstract Objective: To investigate the diagnostic accuracy of 320-slice dynamic volume coronary CT angiography (320-CCTA) in detecting coronary stenosis and to analyze the impact of coronary calcium in different calcification burden groups. Methods: The retrospective analysis enrolled 161 cases undergoing 320-CCTA and thereafter invasive coronary angiography (CAG) within 4 weeks for suspected coronary artery disease. Compared to CAG, the pretest probability of coronary stenosis was analyzed; the receiver operation characteristic (ROC) curve and area under curve of ROC (AUC) were used for statistical analyses. Results: Of 161 patients, 121 cases (75.2%) with optimal imaging quality (scale 4), 40 patients (24.8%) with adequate quality (scale 3). No any stair-step artifact or motion artifact in all cases. A total of 182 (7.9%) segments had some degree of calcification, of all segments, 136 (5.9%) had lightly calcification, 39 (1.7%) had moderate calcification, 7 (0.3%) had severely calcification. The sensitivity and specificity of 320-CCTA for detecting coronary stenosis were at least 50%: noncalcified plaque group (NCP) 98.3%, 81.3%, mixture plaque group (MP) 100%, 86.2%, lightly calcified plaque group (LCP) 78.6%, 99.2%, moderately calcified plaque group (MCP) 90%, 86.2%, severely calcified plaque group (SCP) 100%, 66.7%, the AUC was 0.90, 0.93, 0.89, 0.88, 0.83, respectively. Conclusion: Generally 320-CCTA provides high diagnostic accuracy; but the accuracy will be decreased due to severely calcification.

Key words： tomography, x-ray computed coronary angiography plaque AUC

Received: 14 October 2014

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	XIE Furong
	XU Huazhi
	JIANG Yiyi
	CAO Guoquan
	WU Enfu

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2015/V45/I8/570

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