富含缓释淀粉高单不饱和脂肪酸型肠内营养制剂对糖耐量异常患者糖脂代谢的影响

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Abstract Objective: To investigate the effects of enteral nutrition containing slow-release starch and high-monounsaturated-fat on blood and lipid metabolism in patients with impaired glucose tolerance. Methods: Sixty-two patients with impaired glucose tolerance from out-patient clinic were randomized to experimental meal group (Abbott Glucerna SR, n=32) and common breakfast group (isocaloric normal oral diet, n=30), the fasting plasma glucose, 2-hour postprandial plasma glucose, fasting insulin, 2-hour postprandial insulin, serum lipid profile were examined before and after 4-week intervention, and the parameters were compared within groups and between groups. Results: The 2-hour postprandial plasma glucose, postprandial serum insulin, serum triglyceride, total cholesterol and low-density lipoprotein cholesterol significantly decreased in experimental meal group (P<0.05 or P<0.01), when compared with that of baseline; After 4-week intervention, these parameters were statistically lower than that in common breakfast group (P<0.01 or P<0.05). Conclusion: Dietary consumption of slow-release starch and high-monounsaturated fat can improve glucose metabolism and lipid control in patients with impaired glucose tolerance.

Key words： slow-release starch monounsaturated fatty acid impaired glucose tolerance lipids blood glucose

Received: 04 September 2014

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	Articles by authors
	WU Wenjun1
	XIANG Songying2
	SHEN Feixia1
	WANG Yi3
	CHEN Xiong1
	GU Xuemei1.

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2015/V45/I1/6

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