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| Clinical application of low dose research for coronary CT angiography with 320-slice volume CT |
Department of Radiology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015
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CAI Chuyi,CAO Guoquan,HU Hao, et al. Clinical application of low dose research for coronary CT angiography with 320-slice volume CT[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2014, 44(5): 352-.
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Abstract Objective: To evaluate and compare the image quality and radiation dose of coronary computed tomography angiography (CCTA) received by prospective ECG-gated CTA mode with tube current modulated CFA mode on 320-slice volume CT. Methods: Ninety-seven patients with suspected coronary artery disease were randomly divided into two groups: 53 consecutive patients were performed CCTA with tube current modulated CFA mode (group A) and 44 patients with prospective electrocardiographic gating (group B). Evaluating coronary artery by subjective and objective judgements, the image quality of CCTA were subjectively evaluated using a 4-point scale, while objectively evaluated by comparing mean intraluminal attenuation (SI), noise (SD), signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) of the ascending aorta. The image quality of coronary artery between groups was compared by Mann-Whitney U test, and the radiation dose between groups was compared by t test. Results: The average radiation dose was (8.66±3.67) mSv in group A and (3.99±2.42) mSv in group B, with significant difference for A vs B (t=-7.503, P<0.05). Of 1187 coronary artery segments in group A and B, good image quality (score of 3 or 4) was achieved in 92.4% (599∕648) in group A, 92.9% (501/539) in group B, with no significant difference for A vs B (Z=-0.480, P=0.631). The values of SI, SD, SNR, CNR in group A were (433.4±82.5)HU, (22.1±6.2), (20.7±5.7), (16.6±5.0), and the values of SI, SD, SNR, CNR in group B were (436.1±94.7) HU, (21.5±4.9), (20.9±5.5), (16.9±4.7). There was no significant difference of the image quality between group A and B objectively (P>0.05). Conclusion: 54% radiation dose of CCTA is reduced in 320-slice volume CT scan by using prospective ECG-gated CTA mode, moreover, the diagnostic quality of the image is also ensured.
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Received: 17 September 2013
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2014, Vol. 44 
