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The correlative analysis between atherosclerosis of head and neck large arteries and leukoaraiosis |
Department of Neurology, Zhoushan Hospital Affiliated to Wenzhou Medical University, Zhoushan, 316004
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Cite this article: |
LV Yanghui,HE Songbin,TANG Weiguo, et al. The correlative analysis between atherosclerosis of head and neck large arteries and leukoaraiosis[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2014, 44(12): 872-876.
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Abstract Objective: To explore the correlation between large artery atherosclerosis (LAA) and leukoaraiosis (LA), that the assessment of LAA and LA were using by DSA and cranial MRI. Methods: A total of 231 cerebral infarction or TIA patients were enrolled, all of them were underwent cranial MRI and DSA examinations. The cerebral vascular risk factors were also collected. According to the Fazekas scale, all patients were divided into two groups, the “significant LA” group and the “little or no LA” group. A univariate and logistic regression analysis were used to determine the independent risk factors for LA. Results: The highest correlation was found between carotid artery stenosis and LA (r=0.30, P<0.001). Age (OR value 1.11, 95%CI 1.07-1.15; P<0.001), hypertension (OR value 3.64, 95%CI 1.61-8.20, P=0.002), moderate carotid stenosis (OR value 4.49, 95%CI 1.54-13.13, P=0.006) and severe carotid stenosis (OR value 4.29, 95%CI 1.69-10.90, P=0.002) were independent risk factors for LA. Conclusion: There is a close correlation between LAA and LA, carotid artery stenosis was an independent risk factors for LA.
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Received: 14 February 2014
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