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| Liver abscess in the elderly: clinical features and outcomes |
| WU Zhenzhu1, CHEN Yi2, SUN Haoyue2,PAN Juyi2, YE Yi2. |
| 1.Department of Infectious Disease, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China; 2.Department of Gastroenterology, Wenzhou People’s Hospital, Wenzhou 325000, China |
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| Cite this article: |
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WU Zhenzhu,CHEN Yi,SUN Haoyue, et al. Liver abscess in the elderly: clinical features and outcomes[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2022, 52(9): 724-728,735.
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Abstract Objective: To analyze the clinical characteristics in the elderly with liver abscess (LA) so as to provide reference for clinical diagnosis and treatment. Methods: Clinical data of patients with liver abscess from the Second Affiliated Hospital of Wenzhou Medical University and the Wenzhou People’s Hospital from 2017 to 2020 were collected. They were divided into two groups according to their age: the old group (≥65 years old) and the young group (<65 years old). Then clinical data such as the demographic characteristics, clinical characteristics, laboratory and imaging results, etiological characteristics, complications, treatment and prognosis were compared. Results: Of totally 408 patients in the study, 200 patients (49.0%) were in the old group and 208 (51.0%) in the young group. There were more females in the old group than in the young group (46.0% vs. 29.8%,P=0.001). Old patients were more likely to have biliary diseases (45.0% vs. 28.8%, P=0.001), hypertension (61.0% vs. 29.3%, P<0.001) and hyperuricemia (6.5% vs. 1.9%, P=0.025). In terms of imaging features, 5-10 cm and single liver abscess was most common in both groups. Klebsiella pneumoniae was the most common pathogen, and there was no difference in pathogens distribution between the two groups (P>0.05). There was no difference in the treatment options for the old group, and antibiotics combined with aspiration or drainage were most common in both groups. In terms of complications, the hospital mortality between the two groups was similar,but the old group were more likely to be complicated with pleural effusion and acute renal insufficiency, often
requiring longer hospitalization (P<0.05). Conclusion: The clinical characteristics of the elderly with LA are lack of specificity but the incidence of female patients is higher, with more complications. Klebsiella pneumoniae was the most frequent bacterium. Properly treated, old patients with LA can have comparable outcomes as the young,but require a longer hospital stay.
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Received: 18 May 2022
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