胃癌术后并发症对5年生存率的影响

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Abstract Objective: To investigate the potential impact of postoperative complications on 5-year survival after gastrectomy for gastric cancer. Methods: A total of 380 gastric cancer patients with complete follow-up data who underwent gastrectomy between January 2006 and April 2009 in the First Affiliated Hospital of Wenzhou Medical University were enrolled in this study. Patients were devided into 2 groups: with (n=52) or without (n=328) complications after surgery. The types and classifications of postoperative complications were assessed to analyze the risk factors affecting the occurrence of postoperative complications and the impact of postoperative complications on 5-year survival. Results: In the univariate analysis, age, body mass index (BMI), depth of invasion, lymph node metastasis, TMN staging were significant predictors of postoperative complications and age, gender, depth of tumor invasion, lymph node metastasis, distant metastasis, TMN staging, surgical approach, differentiation of tumor and postoperative complications were significantly related to the 5-year survival of patients (P<0.05). Mutivariate analysis based on COX proportional hazard regression model showed that postoperative complications, gender, lymph node metastasis and tumor differentiation were independent prognostic factors on 5-year survival. Conclusion: Postoperative complications after gastric resection is one of the independent factors in patients on 5-year survival, and active prevention and treatment of postoperative complications is of great significance to prolong living time.

Key words： gastric neoplasms postoperative complications 5-year survival

Received: 07 August 2014

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	Articles by authors
	MA Haiguang
	HU Changyuan
	PANG Wenyang
	JIN Jinji
	CHEN Jiaozhen
	JIN Cancan
	CHEN Wenjing
	ZHU Guanbao.

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2014/V44/I11/787

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