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Comparative analysis of multislice spiral CT characteristics between pulmonary disease due to mycobacterium avium-intracellularis and multi-drug resistant tuberculosis |
ZHOU Rongzhen, WU Xiuli,WANG Jian, YANG Hai, JI Wenbin |
Department of Radiology, Taizhou Hospital, Wenzhou Medical University,Taizhou 317000, China |
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Cite this article: |
ZHOU Rongzhen,WU Xiuli,WANG Jian, et al. Comparative analysis of multislice spiral CT characteristics between pulmonary disease due to mycobacterium avium-intracellularis and multi-drug resistant tuberculosis[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2021, 51(7): 564-569.
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Abstract Objective: To investigate the similarities and differences of imaging features of multislice spiral CT (MSCT) between pulmonary disease due to mycobacterium avium-intracellularis and multi-drug resistant tuberculosis. Methods: The difference of MSCT images between 41 cases of MAC lung disease (MAC group) identified by bacteria and 41 cases of MDR-TB (MDR-TB group) matched by 1:1 was analyzed retrospectively.Statistical analysis was performed. Results: The detection rate of thin-walled cavity in the MAC group was 69.2%,higher than that in the MDR-TB group; average wall thickness in MAC group was 2.5 (1.8, 3.3)mm, while it was 3.9 (2.7, 5.0)mm in MDR-TB group. The differences were all statistically significant (P<0.001). The detection rate of lobular of outer wall of cavity or burr sign, satellite focus of cavity and drainage bronchus in MAC group was 53.8%, 49.2% and 27.7%, respectively, lower than those in the MDR-TB group (79.6%, 93.9%, 67.3%,respectively) with significant differences (P<0.05). The detection rate of bronchiectasis in the MAC group,bronchiectasis involvement range ≥3 lung lobes, right lung middle lobe, left lung tongue lobe, and left lower lobe bronchiectasis detection rate, columnar bronchiectasis, bronchiectasis with lobular central nodules wasrespectively 73.2%, 43.9%, 63.4%, 48.8%, 22.0%, 53.3%, 56.1%, higher than the MDR-TB group (46.3%, 9.8%,12.2%, 2.4%, 4.9%, 21.1%, 24.4% respectively). The differences were statistically significant (P<0.05). The proportion of cystic bronchiectasis in the MAC group (13.3%) was lower than MDR-TB group (47.4%) with statistical difference (P<0.05). The detection rate of nodules/spherical masses in the MAC group > 1 cm was 22.0%, and compared with 68.3% in the MDR-TB group, there was statistical difference (P<0.001). Conclusion:The MSCT manifestations of MAC lung disease and MDR-TB lung disease have their own specificity. The type of cavities, the type of bronchiectasis, dominant location and distribution, and the size of nodules are of differential significance, which are helpful for clinical diagnosis.
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Received: 25 November 2020
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