CT评估的脂肪肝与高脂血症性急性胰腺炎严重程度的相关性

doi:10.3969/j.issn.2095-9400.2021.07.006

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Abstract Objective: To explore the association between CT measured fatty liver and the severity of hyperlipidemic acute pancreatitis (HLAP). Methods: Clinical data from 223 HLAP patients were retrospectively collected. According to the scoring by the modified CT severity index (MCTSI), there were 62 patients with mild HLAP and 161 with moderate to severe HLAP. Based on the liver/spleen CT value ratio, the patients were divided as no-to-mild fatty liver group and moderate-to-severe fatty liver group. Univariate and multivariate logistic regression analyses were used to analyze the independent risk factors of the severity of HLAP. Results: Of the HLAP patients, 184 (82.5%) presented fatty liver. Compared with patients with no or mild fatty liver, patients with moderate-to-severe fatty liver had a higher probability of hospitalization by more than 2 weeks (55.7% vs.39.3%, P<0.05). Compared with the mild HLAP group, the average triglyceride (TG) level of patients in the moderate-to-severe HLAP group was significantly higher (P<0.01), while the liver/spleen CT value ratio was significantly lower (P<0.01). There were no significant differences in body mass index, waist circumference,muscle area, subcutaneous fat area, visceral fat area, visceral fat area/total fat area between the two groups (all P>0.05). Univariate Logistic regression analyses showed that a co-existence of moderate-to-severe fatty liver and a high TG level were risk factors for moderate-to-severe HLAP (both P<0.05). After adjustment by multivariate Logistic regression analyses, the presentation of moderate-to-severe fatty liver was still an independent risk factor for moderate-to-severe HLAP (P<0.05). In addition, after treatment, 67.0% of the moderate-to-severe fatty liver presented in the HLAP patients were normalized to no or mild fatty liver. Conclusion: The severity of fatty liver assessed by CT was associated with the severity of HLAP patients and the length of hospitalization.

Key words： hyperlipidemic acute pancreatitis fatty liver modified CT severity index computed tomography X-ray

Received: 15 November 2020

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	CHEN Lifang
	YU Huajun
	HUANG Yingbao
	SUN Wenna
	SUN Hongwei
	JIN Yin
	WU Enfu

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https://xb.wmu.edu.cn/EN/10.3969/j.issn.2095-9400.2021.07.006 OR https://xb.wmu.edu.cn/EN/Y2021/V51/I7/554

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