结核毁损肺合并原发肺动脉血栓形成的临床特征

doi:10.3969/j.issn.2095-9400.2021.06.010

Abstract
Figure/Table
References (0)
Related Citation (15)

Download: PDF (1549 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective: To summarize and analyze the clinical characteristics and prognosis of patients with tuberculosis-destroyed lung (TDL) and in-situ pulmonary artery thrombosis (PAT). Methods: Patients with TDL who were hospitalized in Wenzhou Central Hospital from June 2015 to May 2020 were analyzed retrospectively. They were divided as TDL with PAT group and TDL group, according to whether they were complicated with PAT. Data on demographic characteristics, tuberculosis history, imaging information, systolic pulmonary artery pressure (SPAP) and blood gas analysis were collected. Results: Compared with TDL group, patients complicated
with PAT had more damaged lobe lesions (P<0.05). ABG showed higher alveolar-arterial oxygen partial pressure difference. The rate of SPAP > 50 mmHg (moderate and severe pulmonary hypertension) in patients complicated with PAT was 100% (6/6), which was significantly higher (P<0.05) than TDL group19% (4/21). One patient died in TDL with PAT group, wihile none died in TDL group. Conclusion: Patients with TDL who have multiple lobes damaged and moderate to severe pulmonary hypertension should be alert to be complicated with PAT.

Key words： tuberculosis destroyed lung in-situ pulmonary artery thrombosis pulmonary hypertension

Received: 17 January 2021

	Service
	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	CHI Qiong
	ZNENG Jiyang
	DAI Xinjian
	ZHANG Baoyi
	HUANG Yang.

URL:

https://xb.wmu.edu.cn/EN/10.3969/j.issn.2095-9400.2021.06.010 OR https://xb.wmu.edu.cn/EN/Y2021/V51/I6/483

参考文献：
[1] EOM J S, PARK H Y, LEE M K, et al. The effects of bronchodilators in patients with tuberculosis-destroyed lung and chronic airflow obstruction[J]. Eur Respir J, 2015, 46(Suppl 59): PA3941.
[2] KIM S J, LEE J, PARK Y S, et al. Effect of airflow limitation on acute exacerbations in patients with destroyed lungs by tuberculosis[J]. J Korean Med Sci, 2015, 30(6): 737-742.
[3] 项海燕, 唐燕华, 李金, 等. 淤血性肺动脉高压伴原发性肺动脉血栓形成1例[J]. 中华胸心血管外科杂志, 2014, 30(7): 444.
[4] JO Y S, PARK J H, LEE J K, et al. Risk factors for pulmonary arterial hypertension in patients with tuberculosis-destroyed lungs and their clinical characteristics compared with
patients with chronic obstructive pulmonary disease[J]. Int J Chron Obstruct Pulmon Dis, 2017, 12: 2433-2443 .
[5] LAU E M, TAMURA Y, MCGOON M D, et al. The 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: a practical chronicle of progress[J]. Eur Respir J, 2015, 46(4): 879-882.
[6] RHEE C K, YOO K H, LEE J H, et al. Clinical characteristics of patients with tuberculosis-destroyed lung[J]. Int J Tuberc Lung Dis, 2013, 17(1): 67-75 .
[7] 苏秀丽, 王同生, 孙瑜霞, 等. 结核毁损肺合并肺动脉高压的临床特征及危险因素分析[J]. 中华传染病杂志, 2018, 36(8): 498-501.
[8] 洪征, 白连启, 阎东杰, 等. 肺结核全肺切除近期并发症的治疗[J]. 中华结核和呼吸杂志, 2011, 34(8): 582-585.
[9] CHA S I, CHOI K J, SHIN K M, et al. Clinical characteristics of in-situ pulmonary artery thrombosis in Korea[J]. Blood Coagul Fibrinolysis, 2015, 26(8): 903-907.
[10] BROBERG C S, UJITA M, PRASAD S, et al. Pulmonary arterial thrombosis in Eisenmenger syndrome is associated with biventricular dysfunction and decreased pulmonary flow velocity[J]. J Am Coll Cardiol, 2007, 50(7): 634-642.  
[11] KWEK B H, WITTRAM C. Postpneumonectomy pulmonary artery stump thrombosis: CT features and imaging follow-up [J]. Radiology, 2005, 237(1): 338-341.
[12] YILMAZ S, CIMEN K A. Pulmonary artery aneurysms in Behcet’s disease[J]. Rheumatol Int, 2010, 30: 1401-1403.
[13] 中华医学会呼吸病学分会肺栓塞与肺血管病学组. 肺血栓栓塞诊治与预防指南[J]. 中华医学杂志, 2018, 98(14): 1060-1087.
[14] ITO H, NANKA S, ISHIBASHI T. Extensive pulmonary arterial thrombi in situ in association with atrial septal defect [J]. Circ J, 2003, 67(7): 640-642.