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| Correlation between osteocalcin and coronary artery disease: a cross-sectional study |
| MA Jun, GUAN Xueqiang |
| Department of Cardiology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China |
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| Cite this article: |
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MA Jun,GUAN Xueqiang. Correlation between osteocalcin and coronary artery disease: a cross-sectional study[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2020, 50(12): 998-1002.
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Abstract Objective: To investigate the relationship between osteocalcin (OC) and the angiographically demonstrated coronary artery disease (CAD). Methods: A total of 317 consecutive patients with stable chest pain suspected of CAD underwent elective coronary angiography (CAG). The association between OC and CAD was analyzed. Results: An inverse association was displayed between OC and CAD. Compared with lowest OC level,the highest OC level was related with lower CAD risk (P<0.01). After adjustment of traditional coronary risk factors, OC was an independent predictor of CAD (OR=0.93, 95%CI=0.90-0.96, P<0.01). Conclusion: Among older patients suspected of CAD, higher OC indicated an decreased CAD risk. OC was an independent predictor of CAD.
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Received: 27 March 2020
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