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| Investigation of TCM constitution of HLA-B27-associated acute anterior uveitis |
| JIANG Xiaohan, LI Yan, WANG Yuqin, LU Chunjie, ZHAO Yingxi, XIANG Shengjin. |
| Department of Chinese Ophthalmology, Eye Hospital of Wenzhou Medical University, Wenzhou 325027, China |
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| Cite this article: |
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JIANG Xiaohan,LI Yan,WANG Yuqin, et al. Investigation of TCM constitution of HLA-B27-associated acute anterior uveitis[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2020, 50(9): 758-761.
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Abstract Objective: To investigate and summarize the characteristics and distribution patterns of Chinese Traditional Medicine (TCM) constitution in quiescent stage of acute anterior uveitis patients with HLA-B27 positive, so as to provide more theoretical information for clinical prevention and treatment. Methods: There were 322 patients of acute anterior uveitis in quiescent stage included in this study. The participants were divided into HLA-B27(+) group and HLA-B27(-) group according to HLA-B27 gene test results, and their TCM constitution characteristics and distribution were analyzed. Results: Of all 332 patients, there were 295 cases of single constitution type and 37 cases of combined constitution with 75 physical types, which meant a total of 332 patients with 370 constitution types in this study. Of the 185 cases of HLA-B27(+) patients, the constitution type of single physical, mild physical, pathological physical and complex physical were 164, 98, 66 and 21 cases, respectively. The complex physical type contained 43 different kinds of physical types. In contrast, of the 147 cases of HLA-B27(-) patients, the constitution type of single physical, mild physical, pathological physical and complex physical were 131, 97, 34 and 16 cases, respectively. The complex physical type contained 32 different kinds of physical types. Therefore, HLA-B27(+) group had a higher proportion of pathological constitution and damp heat constitution, which showed statistical significance between them (P<0.05). Conclusion: HLA-B27-associated acute anterior uveitis is a disease with similar physical susceptibility, but in quiescent stage mild physical constitution
is dominated. Compared with HLA-B27(-) patients with acute uveitis, the pathological constitution overall proportion of patients with HLA-B27(+) patients with acute uveitis was higher, and there were more patients with damp-heat constitution.
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Received: 27 June 2019
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