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| The association between functional liver volume and liver function evaluated by quantitative analysis of gadoxetic acid-enhanced magnetic resonance imaging |
| CAI Jiale1, WANG Zhaohong2, CHEN Hui2, TONG Hongfei2 |
1.School of Nursing, Wenzhou Medical University, Wenzhou 325035, China; 2.Department of Hepatobiliary Surgery, the Second Affiliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, China
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| Cite this article: |
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CAI Jiale,WANG Zhaohong,CHEN Hui, et al. The association between functional liver volume and liver function evaluated by quantitative analysis of gadoxetic acid-enhanced magnetic resonance imaging[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2020, 50(8): 637-641.
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Abstract Objective: To compare correlations between FLV and Child-Pugh classification of liver function. Methods: All 25 patients with liver cirrhosis performed enhanced CT and Gd-EOB-DTPA-enhanced MRI were recruited in this study. The liver function of all cases was evaluated by Child-Pugh classification. The contrast enhancement ratio (CER) was analyzed by SIlh-SIlu/SIlu, and the volume of each liver segment measured by MI-3DVS. Then correlations between anatomical liver volume, functional liver volume and Child-Pugh classification of liver function analyzed. Results: Analyses showed that Child-Pugh classification of liver function was negatively correlated to the ALV (r=-0.792, P<0.001), with determination coefficient of curve fitting (R2=0.63); Child-Pugh classification of liver function was also negatively correlated with FLV (r=-0.911, P<0.001), determination coefficient of curve fitting (R2=0.80). Compared between the two analyzing methods of liver volume, FLV had more significant negative correlation with Child-Pugh classification of liver function. Conclusion: The FLV calculated by CER of Gd-EOB-DTPA-enhanced MRI combined with ALV from MI-3DVS could better reflect the liver function than ALV.
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