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| Preparation of acryloyloxyethyl trimethyl ammonium chloride conductive hydrogel and its performance detection |
| XUE Yujie1, XU Lifei1, ZHANG Qilu1, WANG Jiaqian1, XU Ke2, LIN Luyang3 |
| 1.School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China; 2.The Institute of Life Sciences, Wenzhou University, Wenzhou 325000, China; 3.Department of Emergency, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China |
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| Cite this article: |
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XUE Yujie,XU Lifei,ZHANG Qilu, et al. Preparation of acryloyloxyethyl trimethyl ammonium chloride conductive hydrogel and its performance detection[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2020, 50(8): 623-627.
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Abstract Objective: To screen out the optimal formulation of hydrogels with excellent mechanical properties and electrical conductivity. Methods: A composite conductive hydrogel was prepared by using acryloyloxyethyl trimethyl ammonium chloride (DAC) as the main matrix, N, N-methylenebisacrylamide (BisAAm) as the chemical cross-linking agent, and 1-hydroxycyclohexyl benzophenone as the catalyst, added with glycerol and hydroxyethyl cellulose (HEC). Its conductivity, viscosity, tensile properties and compression properties were measured. Results: After using DAC as the matrix and adding BisAAm, glycerin, and HEC in proportion, the gel had no odor or residue compared with 3M conductive hydrogel, with good long-term stability, without color change and bacterial growth. At the same time, after adding glycerin and HEC by proper proportions, its conductivity, viscosity, tensile properties and compression properties were better than traditional 3M conductive gels. It was found through mouse skin contact experiments that the hydrogels had good biological safety. Conclusion: The hydrogel DAC content is at its best when its content is 60% and the proportion of BisAAm, glycerol and HEC is 5%, 10% and 0.015% respectively.
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