新型冠状病毒肺炎的临床特征、CT表现与动态变化

doi:10.3969/j.issn.2095-9400.2020.03.003

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Abstract Objective: To explore the clinical characteristics, CT manifestations and dynamic changes of patients with corona virus disease 2019 (COVID-19). Methods: A total of 39 patients with COVID-19 from Yongjia County People’s Hospital during January 20 2020 to February 10 2020 were collected, and their clinical and laboratory characteristics, CT manifestations and dynamic changes were retrospectively analyzed. Results: Of 39 COVID-19 patients, 3 were mild, 28 normal and 8 severe; 37 of them had a clear epidemiological history. In the first admission, peripheral blood leukocyte counts decreased in 5 cases, lymphocyte counts decreased in 7 cases, and C-reactive protein levels increased in 18 cases, serum amyloid A levels increased in 35 patients. By the time of discharge, their clinical symptoms were obviously relieved, and laboratory indicators of peripheral blood returned to normal. Pulmonary lesions showed a natural course. On admission, the initial CT manifestations included subpleural patchy, nodular ground glass density shadows, with or without thickening of the lobular septum. 3 to 6 days after admission, the lesions increased, the scope expanded, and the consolidation became obvious, and air bronchus signs were seen. The new lesions showed a thin ground-glass density shadow, and the sub-pleural distribution of the middle and lower lobe of both lungs was dominant. 9 to 11 days after admission, CT showed that the lesion area and density were reduced in mose cases, completely absorbed in 4 cases, and fibrous lesions remained in 3 cases. Conclusion: Certain CT dynamic changes, clinical and laboratory manifestations are characteristic of COVID-19. A deeper understanding of them will make up for the false negative of virus nucleic acid test, so that patients can be early isolated and intervened.

Key words： novel coronavirus pneumonia tomography, X-ray computer

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	YE Xiaoxue
	XIE Yibing
	XU Chongyong
	XU Hui
	YAN Zhihan
	FANG Bidong
	YANG Chaoying
	CHEN Meikui
	CHEN Qi

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https://xb.wmu.edu.cn/EN/10.3969/j.issn.2095-9400.2020.03.003 OR https://xb.wmu.edu.cn/EN/Y2020/V50/I3/182

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