|
|
|
| Observation on effects of the small follicles puncture using Gn 7-9 days in vitro fertilization cycles |
| Department of Reproductive Medicine Center, the Second Affiliated Hospltal of Wenzhou Medical University, Wenzhou, 325027 |
|
| Cite this article: |
|
CHI Hai hong,HUANG Zhaoxia,CHENG Jing, et al. Observation on effects of the small follicles puncture using Gn 7-9 days in vitro fertilization cycles[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2014, 44(9): 657-.
|
|
|
|
Abstract Objective: To observe clinical outcome of the patients with excessive follicular development in controlling ovulation process treating with the small follicles puncture. Methods: Sixty-four infertile women in our center accepted IVF treatment during the period from April 2011 to April 2012 were analyzed retrospectively. All of them had excessive follicular development and had the tendency of ovarian hyperstimulation syndrome (OHSS). They were divided into two groups based on the their wills. The follicle puncture group (n=36) and control group (n=32). The general index, the laboratory and the clinical outcome of the two groups were compared. Results: There were no statistically significant differences in age, time of infertility, basal and the day of follicles puncture hormones level (P>0.05). The day of hCG serum level of estradiol (estrogen, E2) and the number of oocyte retrieved in follicle puncture group was obviously lower than that in control group (P<0.05). The rates of fertilization, cleavage, and clinical pregnancy in follicle puncture group was obviously higher than that in control group (P<0.05). The follicle puncture group had no severe ovarian hyperstimulation, but the severe OHSS occurred in 13 patients (13/32, 40.6%) of control group. Conclusion: The small follicle puncture can effectively reduce the incidence of OHSS and improve the outcome of IVF-ET cycles.
|
|
Received: 15 July 2013
|
| |
|
|
|
[1]Mio Y, Toda T, Tanikawa M, et al. Tramvaginal ultrasound-guided follicular aspiration in the management of anovula-tory infertility associated with polycystic ovaries[J]. Fertil Steril, 1991, 56(6): 1060-1065.
[2]Billig H, Furuta F, Hsueh AIW. Estrogens inhibit and andro-gens enhance ovarian granulosa cell apoptosis[J]. Endocri-nology, 1993, 133: 2204-2212.
[3]赵军招, 叶碧绿, 林金菊, 等. 经阴道小卵泡穿刺术治疗耐克罗米芬多囊卵巢综合征的临床研究[J]. 生殖医学杂志, 2006, 4(15): 81-83.
[4]金仁枫, 刘雨生, 童先宏, 等. 卵母细胞体外成熟预防卵巢过度刺激综合征的应用[J]. 现代妇产科进展, 2007, 16(7): 514-516.
[5]沈庆娟. 不同卵泡发育时间段卵泡抽吸术对多囊卵巢患者的影响[J]. 医学研究, 2011, 10(1): 84-85.
[6]金聪聪, 赵军招, 王真, 等. 体外受精周期中不同改行时机对未成熟卵体外培养结局的影响[J]. 温州医学院学报, 2011, 41(1): 24-27.
[7]Asch RH, Li HP, Balmaceda JP, et a1. Severe ovarian hyer-stimulation syndrome in assisted reproducfive technology of high-risk groups[J]. Hum Reprod, 1991, 6(10): 1395-1399. |
|
|
|
2014, Vol. 44 
