围产期孕妇生殖道B群链球菌感染临床特征

doi:10.3969/j.issn.2095-9400.2019.12.012

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Abstract Objective: To investigate the colonization of obstetric group B streptococcus (GBS) in pregnant women in the late pregnancy and its effect on the pregnancy outcome of perinatal pregnant women. Methods: A total of 3 619 pregnant women who underwent regular check-up in the Second Affiliated Hospital of Wenzhou Medical University from May 2018 to March 2019 were enrolled to be indentified for GBS infection. Query electronic medical records were set up to understand the high maternal risk factors to judge the pregnancy outcome according to clinical diagnosis and routine examination of leucorrhea. Data were analyzed by statistical methods. Results: A comparison between the two groups showed that the history of fungal infection or bacterial vaginitis in GBS-positive group was significantly higher than that in negative group. The results of vaginal secretion test showed that GBS positive maternal vaginal pH increased, cleanliness was worse, and the detection rate of fungi and clue cells was higher (P<0.05, respectively). History of fungal infection and history of bacterial vaginitis were risk factors for GBS infection (P<0.05). According to pregnancy outcome, the incidence of premature rupture of membranes, intrauterine infection and neonatal infection was significantly higher in GBS-positive group (P<0.05). Conclusion: The history of fungal infection or bacterial vaginitis is a high risk factor for GBS infection, which can have adverse effects on maternal and neonatal outcomes and can also have a negative impact on maternal vaginal microenvironment.

Key words： group B streptococcus colonization perinatal outcome pregnant woman

Received: 16 May 2019

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	YANG Xunjun
	DING Hongxiang
	NI Li

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https://xb.wmu.edu.cn/EN/10.3969/j.issn.2095-9400.2019.12.012 OR https://xb.wmu.edu.cn/EN/Y2019/V49/I12/914

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