放射导向定位对乳腺触诊阴性病变的诊断价值研究：Meta分析

doi:10.3969/j.issn.2095-9400.2019.02.009

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Abstract Objective: To evaluate the diagnostic value of radio-guided occult lesion localization (ROLL) for non-palpable breast lesions against wire-guided localization (WGL). Methods: The databases included PubMed, EMBASE, Cochrane Library database, CNKI, WANFANG database. The retrieval time was from the construction of the database to April 2017. In addition, reference documents of related articles were also searched manually. OR(95%CI) were used to evaluate the difference between ROLL group and WGL group, and mean difference (MD) and 95%CI were used to evaluate the difference between ROLL group and WGL group. A subgroup analysis was made according to the type of study design (randomized or nonrandomized study). Sensitivity analysis was performed by the sequential omission of each individual study, and to explore the cause of heterogeneity in the studies. The Egger method was used to test whether there was publication bias. Results: 18 studies (9 RCTs, 9 non-randomized studies) were eligible with ROLL versus WGL compared. Of the trials we included in the meta-analysis, there were a total of 2 370 participants with non-palpable breast lesions [1 297 participants (ROLL); 1 073 participants (WGL)]. The results showed ROLL favorable results in positive excision margins (OR=0.54, 95%CI=0.42-0.70, 1 864 participants, 16 trials), intra-operative re-excision (OR=0.56, 95%CI=0.40-0.79, 1 132 participants, 10 trials) and re-operation rates (OR=0.66, 95%CI=0.48-0.90, 1 569 participants, 11 trials) versus WGL. There were no significant differences in localization complication (OR=0.61, 95%CI=0.24-1.52, 1 375 participants, 11 trials), successful excision (OR=1.13, 95%CI=0.54-2.38, 2 370 participants, 18 trials), postoperative complications (OR=0.82, 95%CI=0.50-1.34, 1 467 participants, 9 trials), specimen volume (MD=-0.76, 95%CI=-6.00-4.47, 686 participants, 4 trials) and operation time (MD=-0.05, 95%CI= -1.07-0.98, 849 participants, 6 trials). Conclusion: Based on this review of the published trials, ROLL may be a method of NPBLs diagnosis in place of WGL.

Key words： non-palpable breast lesions radioguided occult lesion localization wire-guided locali-zation Meta-analysis

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	WU Juan
	XU Xinjian
	ZHU Rui
	JI Wenbin

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https://xb.wmu.edu.cn/EN/10.3969/j.issn.2095-9400.2019.02.009 OR https://xb.wmu.edu.cn/EN/Y2019/V49/I2/117

[1] LOVRICS P J, CORNACCHI S D, FARROKHYAR F, et al. The relationship between surgical factors and margin status after breast-conservation surgery for early stage breast can-cer[J]. Am J Surg, 2009, 197(6): 740-746.
[2] MOMTI S, GALIMBERTI V, TRIFIRO G, et al. Occult breast lesion localization plus sentinel node biopsy (SNOLL): experience with 959 patients at the European Institute of Oncology[J]. Ann Surg Oncol, 2007, 14(10): 2928-2931.
[3] 房瑞林, 张安秦, 洪迎. 钼靶摄片立体定位穿刺乳腺活检的价值[J]. 临床和实验医学杂志, 2009, 8(2): 57-58.
[4] 尹成方, 赵慧娟, 高维仁. X线三维立体定位术诊断临床检查阴性乳腺病变[J]. 中国医学影像技术, 2010, 26(8): 1492-1494.
[5] OCAL K, DAG A, TURKMENOGLU O, et al. Radioguided occult lesion localization versus wire-guided localization for non-palpable breast lesions: randomized controlled trial[J]. Clinics (Sao Paulo), 2011, 66(6): 1003-1007.
[6] MEDINA-FRANCO H, ABARCA-PÉREZ L, GARCÍA-ALVAREZ M N, et al. Radioguided occult lesion localization (ROLL) versus wire-guided lumpectomy for non-palpable breast lesions: A randomized prospective evaluation[J]. J Surg Oncol, 2008, 97(2): 108-111.
[7] BRONSTEIN A D, KILCOYNE R F, MOE R E. Complications of needle localization of foreign bodies and nonpalpable breast lesions[J]. Arch Surg, 1988, 123(6): 775-779.
[8] LUINI A, ZURRIDA S, PAGANELLI G, et al. Comparison of radioguided excision with wire localization of occult breast lesions[J]. Br J Surg, 1999, 86(4): 522-525.
[9] RAMPAUL R S, BAGNALL M, BURRELL H, et al. Randomized clinical trial comparing radioisotope occult lesion localization and wire-guided excision for biopsy of occult breast lesions[J]. Br J Surg, 2004, 91(12): 1575-1577.
[10] JADAD A R, MOORE R A, CARROLL D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary?[J]. Control Clin Trials, 1996, 17(1): 1-12.
[11] LO C K L, MERTZ D, LOEB M. NEWCASTLE-OTTAWA Scale: comparing reviewers’ to authors’ assessments[J]. BMC med res methodol, 2014, 14(1): 45.
[12] EGGER M, SIMTH G D, ALTMAN D G. Systematic reviews in health care: Meta-analysis in context[M]. Second Edition. London: BMJ Publishing Group, 2001: 347-369.
[13] STERNE J A C, GAVAGHAN D, EGGER M. Publication and related bias in meta-analysis: power of statistical tests and prevalence in the literature[J]. J Clin Epidemiol, 2000, 53(11): 1119-1129.
[14] ALIKHASSI A, SAEED F, ABBASI M, et al. Applicability of radioguided occult lesion localization for non-palpable benign breast lesions, comparison with wire localization, a clinical trial[J]. Asian Pac J Cancer Prev, 2016, 17(7): 3185-3190.
[15] DUARTE C, BASTIDAS F, DE LOS REYES A, et al. Randomized controlled clinical trial comparing radioguided occult lesion localization with wire-guided lesion localization to evaluate their efficacy and accuracy in the localization of nonpalpable breast lesions[J]. Surgery, 2016, 159(4): 1140-1145.
[16] GIACALONE P L, BOURDON A, TRINH P D, et al. Radioguided occult lesion localization plus sentinel node biopsy (SNOLL) versus wire-guided localization plus sentinel node detection: a case control study of 129 unifocal pure invasive non-palpable breast cancers[J]. Eur J Surg Oncol, 2012, 38(3): 222-229.
[17] KANAT N B, TUNCEL M, AKSOY T, et al. Comparison of wire-guided localization and radio-guided occult lesion localization in preoperative localization of nonpalpable breast lesions[J]. Turk J Med Sci, 2016, 46(6): 1829-1837.
[18] KREKEL N M, ZONDERHUIS B M, STOCKMANN H B, et al. A comparison of three methods for nonpalpable breast cancer excision[J]. Eur J Surg Oncol, 2011, 37(2): 109-115.
[19] MARISCAL MARTINEZ A, SOLÀ M, DE TUDELA A P, et al. Radioguided localization of nonpalpable breast cancer lesions: randomized comparison with wire localization in patients undergoing conservative surgery and sentinel node biopsy[J]. AJR Am J Roentgenol, 2009, 193(4): 1001-1009.
[20] MORENO M, WILTGEN J E, BODANESE B, et al. Radioguided breast surgery for occult lesion localization-correlation between two methods[J]. J Exp Clin Cancer Res, 2008, 27: 29.
[21] NADEEM R, CHAGLA L S, HARRIS O, et al. Occult breast lesions: a comparison between radioguided occult lesion localisation (ROLL) vs. wire-guided lumpectomy (WGL)[J]. Breast, 2005, 14(4): 283-289.
[22] POSTMA E L, VERKOOIJEN H M, VAN ESSER S, et al. Efficacy of ‘radioguided occult lesion localisation’(ROLL) versus ‘wire-guided localisation’(WGL) in breast conserving surgery for non-palpable breast cancer: a randomised controlled multicentre trial[J]. Breast Cancer Res Treat, 2012, 136(2): 469-478.
[23] RÖNKÄ R, KROGERUS L, LEPPÄNEN E, et al. Radio-guided occult lesion localization in patients undergoing breast-conserving surgery and sentinel node biopsy[J]. Am J Surg, 2004, 187(4): 491-496.
[24] STRNAD P, ROB L, HALASKA M G, et al. Radioguided occult lesion localisation in combination with detection of the sentinel lymph node in non-palpable breast cancer tu-mours[J]. Eur J Gynaecol Oncol, 2006, 27(3): 236-238.
[25] TAKÁCS T, PASZT A, SIMONKA Z, et al. Radioguided occult lesion localisation versus wire-guided lumpectomy in the treatment of non-palpable breast lesions[J]. Pathol Oncol Res, 2013, 19(2): 267-273.
[26] THIND C R, DESMOND S, HARRIS O, et al. Radio-guided localization of clinically occult breast lesions (ROLL): a DGH experience[J]. Clin Radiol, 2005, 60(6): 681-686.
[27] CHU T Y, LUI C Y, HUNG W K, et al. Localisation of occult breast lesion: a comparative analysis of hookwire and radioguided procedures[J]. Hong Kong Med J, 2010, 16(5): 367-372.
[28] 彭庆蓥, 胡大章. 全数字化乳腺X线引导下钙化灶导丝定位活检对早期乳腺癌诊断的意义[J]. 肿瘤基础与临床, 2012, 25(1): 63-64.
[29] 吉华明, 张继, 夏建国. 全数字化X线乳腺钼靶、MRI对乳腺癌的诊断价值探讨[J]. 中华普通外科学文献(电子版), 2013, 7(4): 295-297.
[30] POELLINGER A, DIEKMANN S, DIETZ E, et al. In patients with DCIS: is it sufficient to histologically examine only those tissue specimens that contain microcalcifications? [J]. Eur Radiol, 2008, 18(5): 925-930.
[31] AUDISIO R A, NADEEM R, HARRIS O, et al. Radioguided occult lesion localisation (ROLL) is available in the UK for impalpable breast lesions[J]. Ann R Coll Surg Engl, 2005, 87(2): 92-95.