儿童呼吸科婴儿耐甲氧西林金黄色葡萄球菌鼻定植的危险因素

doi:10.3969/j.issn.2095-9400.2019.02.003

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Abstract Objective: To investigate risk factors of methicillin-resistant staphylococcus aureus (MRSA) nasal colonization in pediatric respiratory department, and to provide reference for clinical intervention. Methods: The cross-sectional study started from April 2017 to March 2018 in pediatric respiratory department of the Second Affiliated Hospital of Wenzhou Medical University. Newly admitted patients were screened daily for their eligibility. For enrolled patients, specimens from nasal vestibule were taken and cultured. The nasal colonization of MRSA and its risk factors were analyzed. Results: A total of 759 infantswere successfully collected specimens. Finally, 492 infants met the entrollment criteria and 46 were found with colonization MRSA (6.1%). Univariate analysis results indicated that MRSA nasal colonization was associated with months of age, delivery mode, history of hospitalization of the family members over the past year and whether any of family members is healthcare provider (P<0.05). Multi-variant logistic regression analysis indicated that over six months of age (OR=0.164, 95%CI: 0.049-0.545) was protective factor, and one of the family members is healthcare provider (OR=9.428, 95%CI: 2.635-33.731), length of hospitalization stay (OR=1.099, 95%CI: 1.008-1.197) were independent risk factors of MRSA nasal colonization. Conclusion: There is a high morbidity of MRSA nasal colonization in patients less than six month of age. The risk factor of colonization is healthcare provider in the family. MRSA nasalcolonization will increase the length of hospitalization stay.

Key words： infants methicillin-resistant staphylococcus aureus colonization risk factors pediatric respir-atory department

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	HANG Shuanghong
	JIA Xiaohui
	WU Yujie
	LYU Junying
	ZHANG Liping

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https://xb.wmu.edu.cn/EN/10.3969/j.issn.2095-9400.2019.02.003 OR https://xb.wmu.edu.cn/EN/Y2019/V49/I2/91

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