计算扩散加权成像对脑肿瘤显示能力的评估

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Abstract Objective: To assess the ability of computed diffusion-weighted imaging (cDWI) to improve the conspicuousness of brain tumors. Methods: Twenty-four patients with brain tumors (15 male and 9 female, ranging from 13 to 73 in age) who had undergone multi-parameters MRI examinations at 3.0T followed by surgery with the interval less than one month were included in this study. 2 b values DWI was used to synthesize images acquired by computed diffusion weighted imaging (cDWI) at b values of 1 500, 2 000, 2 500, 3 000, 3 500, 4 000 s/mm2. Regions of interest (ROIs) were placed on tumor lesions, peritumoral edema regions and normal-appearing white matter regions, respectively. The signal intensity of ROIs were measured and compared. The contrast ratio (CR) between tumor lesions and normal-appearing white matter regions (CRn) and that between tumor lesions and peritumoral edema regions (CRe) in cDWI images were both compared with measured DWI images. Results: The standardized contrast ratios between tumor and peritumoral edema in cDWI images at b values of 2 500, 3 000, 3 500 and 4 000 s/mm2 were significantly higher than that in measured DWI images at b values of 1 000 s/mm2 (mDWI 1 000) (P<0.05). Conclusion: The high b-value cDWI images could enhance the contrast between brain tumor and the peritumoral edema regions, which has showed potential for the detection of peritumoral invasion of malignant tumor.

Key words： brain tumor magnetic resonance imaging computed diffusion weighted imaging

Received: 03 May 2018

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	CHEN Zhongwei
	ZHAO Youfan
	YE Qiong
	ZHANG Zhao
	XUE Yingnan
	CHEN Yongchun
	LI Jiance.

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2018/V48/I10/769

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