胃镜检查中不同镇静与麻醉方案的比较

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Abstract Objective: To assess the advantages and security of three different anesthesia protocols including propofol-sufentanil, propofol-lidocaine aerosol and sufentanil in the outpatient’s gastroscopy procedure. Methods: A total of 240 patients scheduled for gastroscopic examination in Huangyan Hospital Affiliated to Wenzhou Medical University from April 2016 to December 2016 were prospectively randomized into propofol-sufentanil group (PS group), propofol-lidocaine aerosol group (PL group) and sufentanil group (S group). The vital signs (HR, MAP, SpO2) in each group were recorded before anesthesia (T0), before intubation (T1), immediately after intubation (T2) and 5 min after completion of the gastroscopy procedure (T3). The consumption of propofol, the recovery time and adverse effects like body movement, gag reflex, and dizziness were recorded. Results: The dosage of propofol in group PL was significantly lower than in PS group (P<0.01). Compared with PS group, the incidence of body movement in PL group was significantly lower (P<0.05), and the incidence of pharyngeal reflex in PL group and S group was significantly lower (P<0.05). The incidence of tachycardia and hypotension in S group was significantly lower compared with PS group (P<0.05). The recovery time of PL group after the procedure was significantly shorter compared with PS group (P<0.01). Compared with MAP at T0, MAP at T1, T2 and T3 in PS group was lowered (P<0.05) and MAP at T2 in PL group was lowered. Among all the three groups, the MAP level at T1 in S group was highest (P<0.05). At T2 and T3, the level of MAP gradually increased with PS group, PL group and S group (P<0.05). Compared with HR at T0 and T1, HR was increased at T2 in S group (P<0.05). Conclusion: Administration of propofol-lidocaine aerosol and sufentanil in sedation and analgesia can be a feasible anesthesia scheme due to its safety and effectiveness.

Key words： gastroscopy lidocaine propofol sufentanil

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	Articles by authors
	GUO Jiantao
	Ye Qianqian
	YE Keping
	YE Qigang
	WANG Wenwei
	Lin Han

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https://xb.wmu.edu.cn/EN/ OR https://xb.wmu.edu.cn/EN/Y2018/V48/I8/591

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