ZHENG Xiangjian,XU Jianmin.. Analysis of related factors of deep venous thrombosis in lower extremity in perioperative period of rectal cancer[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2018, 48(2): 128-130,134.
Abstract：Objective: To analyze the related factors of deep venous thrombosis in lower extremity in perioperative period of rectal cancer. Methods: Three hundred and ninety-three patients treated by rectal-cancer surgery in our hospital from October 2013 to October 2016 were reviewed retrospectively. The clinical data including age, gender, hospital stay, operation time, operation method, occupation, hypertension, coronary heart disease, diabetes, BMI, smoking status, drinking status, postoperative exercises and treatment by postoperative elastic stockings or intermittent pneumatic calf compression were collected and quantitative analysis was made. Results: In this study, 59 patients were included in the DVT group and 334 patients in the Non-DVT group. There was signifcant difference between the two groups (P<0.05) in age (>60 years old), hypertension, occupation type, operation time, smoking status, postoperative exercises, the treatment by postoperative elastic stockings or intermittent pneumatic calf compression. The multivariate analysis showed that age, smoking, hypertension and operation time were independent risk factors (P<0.05). Physical labour, treatment by postoperativeexercises or postoperative elastic stockings and intermittent pneumatic calf compression were protective factors for DVT (P<0.05). Conclusion: Rectal cancer patients with older age (>60 years old), hypertension and longer operation time should pay much attention to the prevention of DVT in perioperative period, and postoperative exercises can be a precautionary measures.
[1] 复旦大学附属中山医院围手术期处理多学科团队. 普外科患者围手术期血栓预防——中山共识(2)[J]. 中国实用外科杂志, 2013, 33(11): 946-948.
[2] Pulmonary embolism after a single-stage, combined anterior and posterior approach lumbar surgery[J]. Pak J Med Sci, 2013, 29(6): 1462-1464.
[3] NICOL M, SUN Y, CRAIG N, et al. Incidence of thromboembolic complications in lumbar spinal surgeryin 1,111 pa-tients[J]. Eur Spine J, 2009, 18(10): 1548-1552.
[4] GUO F, SHASHIKIRAN T, CHEN X, et al. Clinical features and risk factor analysis for lower extremity deep venous thrombosis in Chinese neurosurgical patients[J]. J Neurosci Rural Pract, 2015, 6(4): 471-476.
[5] 纪烈辰, 俞林. 直肠癌术后应用低分子肝素预防静脉血栓性疾病的价值[J]. 中华消化外科杂志, 2013, 12(6): 428- 430.
[6] ZHANG L, LIU X, XUE Y. Analysis of deep venous thrombosis after Gynecological surgery: A clinical study of 498 cases[J]. Pak J Med Sci, 2015, 31(2): 453-456.
[7] PRONK N P, KATZ A S, LOWRY M, et al. Reducing occupational sitting time and improving worker health: the Take-a-Stand Project, 2011[J]. Prev Chronic Dis, 2012, 9: E154.
[8] HEALY B, LEVIN E, PERRIN K, et al. Prolonged work-and computer-related seated immobility and risk of venous thromboembolism[J]. J R Soc Med, 2010, 103(11): 447-454.
[9] CALDWELL K, PRIOR S J, KAMPMANN M, et al. Upper body exercise increases lower extremity venous blood flow in deep venous thrombosis[J]. J Vasc Surg Venous Lymphat Disord, 2013, 1(2): 126-133.
[10] KANG J, JIANG X, WU B. Analysis of risk factors for lowerlimb deep venous thrombosis in old patients after knee arthroplasty[J]. Chin Med J (Engl), 2015, 128(10): 1358-1362.
[11] REN W, LI Z, FU Z, et al. Analysis of risk factors for recurrence of deep venous thrombosis in lower extremities[J].Med Sci Monit, 2014, 20: 199-204.
[12] 黄静, 阳志军, 张洁清, 等. 妇科恶性肿瘤并发深静脉血栓形成的危险因素及预后影响因素分析[J]. 中华妇产科杂志, 2015, 50(10): 762-769.
[13] 陈魁, 史吏, 高涌. 下肢深静脉血栓后综合征的研究及诊疗进展[J]. 中华全科医学, 2012, 10(2): 284-323.
[14] 杨林, 蔡端, 祁光裕. 腹腔镜术后下肢深静脉血栓形成的相关因素分析[J]. 中国普外基础与临床杂志, 2009, 16(6): 425-428.
