The effect of blood pressure parameters on the outcome of the patients with cerebral hemorrhage in the acute stage
FENG Liang1, WANG Zhen1, ZHANG Zheng1, YE Zusen1, NIU Xiaoting1, HAN Zhao2
First Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015; 2.Department of Neurology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027
FENG Liang,WANG Zhen,ZHANG Zheng, et al. The effect of blood pressure parameters on the outcome of the patients with cerebral hemorrhage in the acute stage[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2018, 48(1): 49-52.
Abstract：Objective: To study the effect of blood pressure parameters on the outcome of the patients with cerebral hemorrhage in the acute stage. Methods: Patients admitted in the neurology emergency clinic of the First Affiliated Hospital of Wenzhou Medical University were collected within 6 hours after onset from December 2010 to January 2013. Their blood pressure was recorded, relevant information was collected and all the cases were followed up for 3 months after stroke. Non-conditional logistic regressions analysis was adopted as the statistical method. To study the factors which affected the outcome of the first 7 days and 3 months after stroke. Results: In total 66 cases were analyzed. Multiplicity showed that the patient’s age (P=0.01, OR=1.19, 95%CI=1.04-1.36), the volume of hematoma (P<0.001, OR=1.34, 95%CI=1.12-1.59), the highest systolic pressure in the first 24 hours (P=0.02, OR=1.10, 95%CI=1.02-1.20) and the average systolic pressure in the first 7 days (P=0.01, OR=0.79, 95%CI=0.66-0.94) were the four independent factors associated with the outcome on the seventh days. The ROC curve was used to screen the boundary value, suggesting that the range of blood pressure in 151.5-178.5 mmHg was beneficial to the patients in acute period. The factors of age and the basic NIHSS were the independent factors connected with outcome of 3 months. Conclusion: The highest systolic pressure within the first 24 h (P=0.03, OR=1.09, 95%CI=1.01-1.17) and the average systolic pressure in the first 7 days (P=0.01, OR=1.27, 95%CI=1.07-1.50) could be used as the independent predictors for the outcome of acute stage of patients with cerebral hemorrhage, and a suitable range of blood pressure was beneficial for the outcome of the disease. The parameters of blood pressure could not be used as independent predictors for the outcome of 3 months in patients with cerebral hemorrhage.
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