单次短时七氟烷全身麻醉对0～3岁儿童术后早期智能发育的影响

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摘要目的：探讨单次短时七氟烷全身麻醉对0～3岁儿童术后早期智能发育的影响。方法：采用Gesell发育量表对200例0～3岁儿童进行麻醉前1 d与麻醉后3个月发育情况的评测与对比；再分别选取与麻醉前1 d和麻醉后3个月同龄的正常儿童各200例为对照组I和对照组II。结果：与麻醉前1 d相比较，麻醉后3个月儿童的4个能区发育龄均有不同程度提高（P＜0.001）；麻醉前后各能区的发育商数（DQ）差异均无统计学意义（P＞0.05）。与对照组同龄儿童比较，麻醉前1 d及麻醉后3个月各能区DQ差异均无统计学意义（P＞0.05）。结论：接受单次短时七氟烷全身麻醉对0～3岁儿童术后Gesell发育量表各指标没有明显影响，各能区随着年龄发育均正常

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	黄梦朦
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	胡梦洁
	南洋
	姬斌
	林函
	李军

关键词 ：麻醉, 全身；Gesell发育量表；智能发育

Abstract：Objective: To explore the effect of single short-term sevoflurane general anesthesia on early postoperative intelligence development in children aged 0-3 years. Methods: Gesell development scale was used to evaluate the neurological development (DQ) of 200 children aged 0 to 3 years old 1 day preoperatively and 3 months after operation. Another 200 normal children in the same age range were selected respectively as control group I and control group II which compared and contrasted with those in anesthesia group. Results: Compared with the DQ scores preoperative 1 day, the developmental age (motor, adaptive, verbal, social) of the four energy regions of children increased to varying degrees after 3 months of anesthesia (P<0.001). The difference of DQ scores of four energy regions 1 day preoperatively and 3 months after operation was not statistically significant (P>0.05). There was no significant difference in DQ scores of four energy regions between anesthesia group and control group (P>0.05). Conclusion: A single short-term sevoflurane general anesthesia has no significant effect on the postoperative DQ of Gesell development scales in children aged 0-3 years, and all energy regions are normal development with age.

Key words： anesthesia, general Gesell development schedule intelligence development

收稿日期: 2017-02-05

基金资助:浙江省医药卫生平台骨干项目（2012ZDA036）。

通讯作者: 李军，教授，主任医师，Email：lijun0068@163.com

作者简介: 黄梦朦（1989-），女，浙江温州人，住院医师，硕士。

链接本文:

https://xb.wmu.edu.cn/CN/ 或 https://xb.wmu.edu.cn/CN/Y2017/V47/I9/670

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