[1] HEIDENREICH A, BASTIAN P J, BELLMUNT J, et al. EAU guidelines on prostate cancer. Part 1: Screening, diagnosis, and local treatment with curative intent-update 2013[J]. Eur Urol, 2014, 65(1): 124-137.
[2] ROEHRBORN C G, PICKENS G J, SANDERS J S. Diagnostic yield of repeated transrectal ultrasound-guided biopsies stratified by specific histopathologic diagnoses and prostate specific antigen levels[J]. Urology, 1996, 47(3): 347-352.
[3] LINDNER J R. Microbubbles in medical imaging: Current applications and future directions[J]. Nat Rev Drug Discov,2004, 3(6): 527-532.
[4] 金慧佩, 赵雅萍, 黄品同, 等. 超声造影在妇科附件良恶性肿块诊断中的应用[J] 温州医科大学学报, 2009, 39(5): 487-489.
[5] 张艳兵, 李丕宏, 卢明东, 等. 双重超声造影与胃增强CT在诊断早期胃癌中的应用[J]. 温州医科大学学报, 2014, 44(8): 585-588.
[6] FREGENE T A, KHANUJA P S, NOTO A C, et al. Tumor-associated angiogenesis in prostate cancer[J]. Anticancer Res, 1993, 13(6B): 2377-2381.
[7] BIGLER S A, DEERING R E, BRAWER M K. Comparison of microscopic vascularity in benign and malignant prostate tissue[J]. Hum Pathol, 1993, 24(2): 220-226.
[8] SEITZ M, GRATZKE C, SCHLENKER B, et al. Contrast-enhanced transrectal ultrasound (CE-TRUS) with cadence-contrast pulse sequence (CPS) technology for the identification of prostate cancer[J]. Urol Oncol, 2011, 29(3): 295-301.
[9] AIGNER F, PALLWEIN L, MITTERBERGER M, et al. Contrast-enhanced ultrasonography using cadence-contrast pulse sequencing technology for targeted biopsy of the prostate[J]. BJU Int, 2009, 103(4): 458-463.
[10] HALPERN E J, FRAUSCHER F, ROSENBERG M, et al. Directed biopsy during contrast-enhanced sonography of the prostate[J]. AJR Am J Roentgenol, 2002, 178(4): 915-919.
[11] XIE S W, LI H L, DU J, et al. Contrast-enhanced ultrasonography with contrast-tuned imaging technology for the detection of prostate cancer: Comparison with conventional ultra-sonography[J]. BJU Int, 2012, 109(11): 1620-1626.
[12] BONO A V, CELATO N, COVA V, et al. Microvessel density in prostate carcinoma[J].Prostate Cancer Prostatic Dis, 2002, 5(2): 123-127.
[13] STRAZDINA A, KRUMINA G, SPERGA M. The value and limitations of contrast-enhanced ultrasound in detection of prostate cancer[J]. Anticancer Res, 2011, 31(4): 1421-1426.
[14] JIANG J, CHEN Y Q, ZHU Y K, et al. Factors influencing the degree of enhancement of prostate cancer on contrast-enhanced transrectal ultrasonography: Correlation with biopsy and radical prostatectomy specimens[J]. Br J Radiol, 2012, 85(1019): e979-e986.
[15] HALPERN E J, MCCUE P A, AKSNES A K, et al. Contrast-enhanced US of the prostate with Sonazoid: Comparison with whole-mount prostatectomy specimens in 12 patients[J]. Radiology, 2002, 222(2): 361-366.
[16] UEMURA H, SANO F, NOMIYA A, et al. Usefulness of perflubutane microbubble-enhanced ultrasound in imaging and detection of prostate cancer: Phase II multicenter clinical trial[J].World J Urol,2013, 31(5):1123-1128.
[17] ZHAO H X, XIA C X, YIN H X, et al. The value and limitations of contrast-enhanced transrectal ultrasonography for the detection of prostate cancer[J]. Eur J Radiol, 2013, 82 (11): e641-e647.
[18] 蔡晓峰, 孙小林, 胡建群, 等. 超声造影对前列腺癌诊断的临床应用研究[J]. 南京医科大学学报(自然科学版), 2008, 28(11): 1461-1464.
[19] JUNG E M, WIGGERMANN P, GREIS C, et al. First results of endocavity evaluation of the microvascularization of malignant prostate tumors using contrast enhanced ultrasound (CEUS) including perfusion analysis: First results[J]. Clin Hemorheol Microcirc, 2012, 52(2-4): 167-177.
[20] PELZER A, BEKTIC J, BERGER A P, et al. Prostate cancer detection in men with prostate specific antigen 4 to 10 ng/mL using a combined approach of contrast enhanced color Doppler targeted and systematic biopsy[J]. J Urol, 2005, 173(6): 1926-1929.
[21] ROY C, BUY X, LANG H, et al. Contrast enhanced color Doppler endorectal sonography of prostate: Efficiency for detecting peripheral zone tumorsand role for biopsy procedure[J]. J Urol, 2003, 170(1): 69-72.
[22] WONDERGEM N, DE LA ROSETTE J J. HIFU and cryoablationle-non or minimal touch techniques for the treatment of prostate cancer. Is there a roal for contrast enhanced ultrasound?[J]. Minim Invasive Ther Allied Technol, 2007, 16(1): 22-30.
[23] ECKERSLEY R J, SEDELAAR J P, BLOMLEY M J, et al.Quantitative microbubble enhanced transrectal ultrasound as a tool for monitoring hormonal treatment of prostate carcinoma[J]. Prostate, 2002, 51(4): 256-267.
[24] PIETERS B, WIJKSTRA H, VAN HERK M, et al. Contrast enhanced ultrasound assupport for prostate brachytherapy treatment planning[J]. J Contemp Brachytherapy, 2012, 4(2): 69-74.
[25] MITTERBERGER M, AIGNER F, PINGGERA G M, et al. Contrast-enhanced colour Doppler-targeted prostate biopsy: Correlation of a subjective blood-flow rating scale with the histopathological outcome of the biopsy[J]. BJU Int, 2010,106(9): 1315-1318.
[26] KUENEN M P, MISCHI M, WIJKSTRA H. Contrast ultrasound diffusion imaging for localization of prostate cancer[J]. IEEE Trans Med Imaging, 2011, 30(8): 1493-1502.
[27] SCHNEIDER M. Molecular imaging and ultrasound-assisted drug delivery[J]. J Endourol,2008, 22(4): 795-802.
[28] 张景瑶, 周晓东, 罗文, 等. 载5-氟尿嘧啶肿瘤靶向超声微泡的制备及其初步评价[J]. 中国超声医学杂志, 2013, 29 (7): 651-655.
[29] 谢鑫, 姜庆, 梁培禾, 等. 携HSV1-TK自杀基因超声微泡造影剂联合前药更昔洛韦对前列腺癌细胞的抑制[J]. 第三军医大学学报, 2012, 34(3): 1285-1288.
[30] VAN HOVE A, SAVOIE P H, MAURIN C, et al. Comparison of image-guided targeted biopsiesvs.systematic randomized biopsies in the detection of prostate cancer: A systematic literature review of well-designed studies[J]. World J Urol, 2014, 32(4): 847-858.