Early identification of neutrophil-to-lymphocyte ratio for severe coronary artery stenosis in patients with chest pain
BAI Hongyuan1, WANG Xiqiang2, WANG Tingzhong2, YANG Dandan2, NING Feifei2, BAI Ruhai3.
1.Department of Cardiology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, 710000; 2.Department of Cardiology, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710000; 3.Department of Epidemiology and Statistics, Xi’an Jiaotong University Health Science Center, Xi’an, 710000
BAI Hongyuan,WANG Xiqiang,WANG Tingzhong, et al. Early identification of neutrophil-to-lymphocyte ratio for severe coronary artery stenosis in patients with chest pain[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2017, 47(4): 282-285.
Objective: To investigate the early identification of NLR for severe coronary artery stenosis in patients with chest pain. Methods: Clinical data of 484 patients who had undergone coronary angiography owing to pectoris symptom were retrospectively analyzed. Patients were divided into severe stenosis group and mild stenosis group based on Gensini scores. Logistic regression and receiver operator characteristic curve were used to analyze early identification of NLR for coronary artery stenosis. Results: Using multiple logistic regression analysis, advanced ages (OR=1.033, 95%CI: 1.013-1.054, P=0.001), male (OR=1.750, 95%CI: 1.062-2.883, P=0.028), LDL-C (OR=1.723, 95%CI: 1.232-2.411, P=0.001), and NLR (OR=1.345, 95%CI: 1.205-1.500, P<0.001) emerged as independent identification for the severe coronary artery stenosis. In receiver operating characteristics curve analysis, NLR>2.32 had 78.5% sensitivity and 62.6% specificity in identify the severity of coronary artery stenosis. Conclusion: High NLR is a powerful identification for the sverity of coronary artery stenosis in patients with chest pain.
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