XU Wen,ZHOU Yongjin,HUANG Xiaoyan, et al. Early diagnostic value of DWI in neonatal cerebral infarction[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(11): 835-839.
Abstract：Objective: To explore the clinical feature and the applied value of diffusion weighted imaging (DWI) in neonatal cerebral infarction (NCI). Methods: The imaging studies and clinical records of eight newborn infants with cerebral infarction were reviewed. All patients underwent conventional MRI and DWI examination, seven patients had a follow up, three patients received a follow-up conventional MRI and DWI scan. Results: All the patients were full term infants, 4 patients had perinatal risks. Seven patients presented seizure as their major symptoms. All cases were misdiagnosed before MRI examinations. Five cases were in acute phase, 2 cases in sub-acute phase, and 1 case in chronic phase. All patients had unilateral infarction, the cortices was involved in 5 cases, the basal ganglia regions in 4 cases, periventricular areas in 2 cases, and the centrum semiovale in 1 case. The infarction areas showed hyperintensity on DWI in acute phase, and showed hypointensity in sub-acute and chronic phase. At follow-up, 7 cases had good prognosis, and the lesions of 3 cases showed persistent hypointensity on DWI. Conclusion: Seizure is the most common primary symptom of NCI, it is easily misdiagnosed without imaging studies, and the definite diagnosis requires early MRI examination. DWI can show the infarction and involvement areas in acute state, and this will provide important clue for the prognostic prediction.
