The clinical value of MRI whole body diffusion weighted imaging in diagnosis of multiple myeloma#br#
ZHANG Zhijing1, ZHENG Wenlong2, DUAN Weimin2, MAO Chuanwan1, YU Zhikang1, YAN Zhihan1, WU Aiqin1.
1.Department of Radiology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027; 2.Department of Radiology, the Affiliated Cangnan Hospital of Wenzhou Medical University, Wenzhou, 325800
ZHANG Zhijing,ZHENG Wenlong,DUAN Weimin, et al. The clinical value of MRI whole body diffusion weighted imaging in diagnosis of multiple myeloma#br#[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(11): 822-825.
Abstract：Objective: To investigate the application value of MRI whole body diffusion weighted imaging (WBDWI) in diagnosis of multiple myeloma. Methods: Twenty one patients with multiple myeloma were underwent WBDWI by GE Signa HDxt 3.0T MR scaner. The positive results were diagnosed and analyzed by double-blind method, and the apparent diffusion coefficient (ADC) values of the lesions were measured on ADC imaging. Results: The diffuse infiltration of bone marrow were demonstrated in all cases of multiple myeloma on WBDWI images. The lesions mainly occurred in the sternum, ribs, vertebrae, pelvis and upper segment of the femur. The lesions showed mottled and patchy hyperintensity on MIP imaging, hypointensity on flipped imaging and ADC imaging. Of 7 cases with follow-up examination after treatment, 6 cases showed that the number of lesions reduced and the signal intensity decreased on MIP imaging, and the ADC values increased. Conclusion: As a new functional MR imaging technology, WBDWI has some application value in diagnosis and therapy evaluation of the multiple myeloma.
