Correlation between abdominal adipose tissue thickness and lumbar disc degeneration: A study based on magnetic resonance imaging
HUANG Kaiyu1, HE Jiawei2, YANG Lili2.
1.Department of Cardiology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027; 2.Department of Radiology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027
HUANG Kaiyu,HE Jiawei,YANG Lili. Correlation between abdominal adipose tissue thickness and lumbar disc degeneration: A study based on magnetic resonance imaging[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(10): 734-737,742.
Abstract：Objective: To investigate the correlation between abdominal adipose tissue thickness and lumbar disc degeneration. Methods: A total of 1 108 inpatients were enrolled from the Second Affiliated Hospital of Wenzhou Medical University between October 2008 and September 2013. Parameters of abdominal adipose tissue thickness based on MRI included abdominal diameter (AD), sagittal diameter (SAD), ventral subcutaneous thickness (VST), and dorsal subcutaneous thickness (DST). Improved Pfirrmann grading system was adopted to evaluate the degree of lumbar disc degeneration. Results: Spearman correlation analysis revealed that SAD and AD had significant associations with disc degeneration score sum (r=0.20, P<0.001; r=0.19, P<0.001) in females. There was negative correlation between VST and disc degeneration score sum (r=-0.10, P=0.01) in males. Ordinal logistic regression showed that SAD (OR=1.14, 95%CI: 1.08～1.20, P<0.001) and AD (OR=1.15, 95%CI: 1.08～1.23, P<0.001) were risk factors of disc degeneration in females; VST (OR=0.70, 95%CI: 0.55～0.89, P=0.003) decreased the risk of disc degeneration in males. Conclusion: AD, SAD and VST are associated with lumbar disc degeneration, and parameters of abdominal adipose tissue thickness based on MRI may be early markers for screening lumbar disc degeneration.
