1.Department of Radiology, the Sceond Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027; 2.Department of Radiology, Jingzhou Central Hospital, Jingzhou, 434020; 3.Department of Neonatology, Jingzhou Central Hospital, Jingzhou, 434020
XU Lei,XIONG Shan,CHENG Jianmin, et al. Applied research of iterative reconstruction technique in the low-dose chest CT scans of children[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(10): 716-719.
Abstract：Objective: To explore the feasibility of low tube current combined with iDose4 iterative reconstruction technique in the low-dose chest CT scans of children. Methods: Eight-eight children continuously underwent routine chest CT scan were divided into two groups using conventional dose (50 mAs) and low dose (25 mAs) scan, respectively. Routine dose group underwent filtered back projection (FBP) reconstruction, record as group A, low dose group was performed FBP, iDose4-1, iDose4-3, iDose4-5 iteration reconstruction (IR), and so referred to as group B, C, D, E. Measured and calculated CT value, noise, signal to noise ratio of each group images in order to evaluate the quality of the images objectively; quality of images was assessed according to five levels rating method by two diagnostic radiology physicians of deputy chief physician title; recorded volume CT dose index (CTDIVOL) and dose length product (DLP) provided by CT scanner dose reports, and calculated the effective dose (ED). Subjective and objective images quality and radiation dose were statistically analyzed. Results: Compared with routine dose group, effective dose (ED) of low dose group decreased by 52%. Subjective and objective quality of images of group B, the worst quality of low dose groups, was less than that of routine dose group (P<0.05), subjective and objective quality of images of group C was less than that of routine dose group (P<0.05), no significant statistical difference was existed between group D and group A in subjective and objective quality of images (P>0.05), subjective and objective quality of images of group E was better than that of group A (P<0.05). Conclusion: When low-dose chest CT scans of children are taking, 25 mAs tube current combined with iDose4-3 iterative reconstruction technique can obtain the same quality of images as routine dose group, while the radiation dose is reduced by 52%.
[1] Pearce M S, Salotti J A, Little M P, et al. Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study [J]. Lancet, 2012, 380 (9840): 499-505.
[2] Kordolaimi S D, Argentos S, Stathis G, et al. Radiation dose and image noise evaluation in coronary computed tomography angiography (CCTA) using an iterative reconstruction algorithm[J]. Hellenic J Cardiol, 2014, 55(3):184-190.
[3] Leipsic J, Nguyen G, Brown J, et a1. A prospective evaluation of dose reduction and image quality in chest CT using adaptive statistical iterative reconstruction[J]. AM J Roentgenol, 2010, 195(5): 1095-1099.
[4] Thomas K E, Wang B. Age-specific effective doses for pediatric MSCT examinations at a large children’s hospital using DLP conversion coefficients: a simple estimation method[J]. Pediatr Radiol, 2008, 38(6): 645-656.
[5] Paolicchi F, Faggioni L, Bastiani L, et al. Optimizing the balance between radiation dose and image quality in pediatric head CT: findings before and after intensive radiologic staff training[J]. Am J Roentgenol, 2014, 202(6): 1309-1315.
[6] Willemink M J, de Jong P A, Leiner T, et al. Iterative reconstruction techniques for computed tomography Part 1: technical principles[J]. Eur Radiol, 2013, 23(6): 1623-1631.
[7] Yoon H, Kim M J, Yoon C S, et al. Radiation dose and image quality in pediatric chest CT: effects of iterative reconstruction in normal weight and overweight children[J]. Pediatr Radiol, 2015, 45(3): 337-344.
[8] 刘琴, 侯阳, 赵鹏飞, 等. 迭代重建技术在小猪胸部容积CT扫描中的应用及最佳剂量研究[J]. 中华放射学杂志, 2014, 48(4): 328-332.
