The clinical features and prognosis of primary peripheral small-sized lung cancer
ZHANG Yongkui1,2, TAN Linlin2, LE Hanbo1,2, WANG Shanjun2, WANG Zhaoyu2, ZHU Wangyu2.
1.Department of Cardiothoracic Surgery, Zhoushan Hospital Affiliated to Wenzhou Medical University, Zhoushan, 316012; 2.Lung Cancer Research Center, Zhoushan Hospital Affiliated to Wenzhou Medical University, Zhoushan, 316012
ZHANG Yongkui,TAN Linlin,LE Hanbo, et al. The clinical features and prognosis of primary peripheral small-sized lung cancer[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(6): 408-412.
Abstract：Objective: To investigate the occurrence and clinical pathologic characteristics of different tumor size (dimension of 2.0 cm or less) primary peripheral small-sized lung cancer, evaluating the prognosis of patients with different tumor size. Methods: The clinical pathologic features and computed tomography (CT) signs of 394 peripheral lung cancer with different tumor size (≤1.0 cm, >1.0～≤1.5 cm and >1.5～≤2.0 cm)were retrospectively analyzed; Statistical analysis was used to analyze the factors of prognosis for patients with small-sized lung cancer. Results: The main subtype of 2 cm or less peripheral lung cancer was adenocarcinoma.The clinical pathologic stage, serum level of carcino-embryonic antigen (CEA), CT signs and subtypes (P<0.05)of peripheral lung cancer with different tumor size had significantly difference; 5-year survival rate of patients with a lung adenocarcinoma of≤1.0 cm was 99.5%, in which the both overall survival time and 5-year survival time were longer than those of the other two groups (P<0.05). Conclusion: Small-sized lung cancer with different tumor size has different clinical pathologic characteristics in which the overall survival time of micro-sized lung cancer patients is longer and the 5-year survival rate is higher, thus the early diagnosis and treatment for patients with micro-sized lung cancer is important.
