Effects of heterologous acellular dermal matrix combined with autologous skin grafts on the residual wounds with titanium mesh in skull defects
LUO Xu1, LIN Cai1, WANG Xinling2.
1.Department of Wounds and Burns Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015; 2.Department of Outpatient Services Center, the Taihe Hospital of Hubei Medical College, Shiyan, 442000
LUO Xu,LIN Cai,WANG Xinling.. Effects of heterologous acellular dermal matrix combined with autologous skin grafts on the residual wounds with titanium mesh in skull defects[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(4): 287-288.
Abstract：Objective: To explore the therapeutic means of heterologous acellular dermal matrix (ADM) combined with autologous skin graft (ASG) to repair the residual skull defective wounds with titanium mesh exposed. Methods: Heterologous acellular dermal matrix (phase I) combined with autologous skin graft (phase II) transplantation operation was used in 10 patients of titanium mesh skull defect with exposed residual wound. The wound heal situation was observed. Results: ADM and ASG were all alive in 10 patients. Healing of type II incision on the wound was in grade I. The average operation duration was 30-45 min, while the average volume of blood loss was 30-50 mL. After follow-up observation for three months, skin elasticity at the surgical transplantation area was good without damage. Conclusion: The new therapeutic method for repairing the residual wound with exposure titanium mesh by means of ADM combined with ASG transplantation can avoid to some extent requiring more working time than other operations, such as regional perforating branch flap and free flap transplantation, and needn’t special equipment, adequate train and the complex preoperative preparation.
