miR-34家族抑制肿瘤作用的研究进展

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摘要 miR-34家族包括miR-34a、miR-34b和miR-34c，广泛分布于节肢动物、线虫纲动物以及哺乳动物中。最近研究发现，miR-34家族可通过多种途径参与肿瘤、心血管疾病和衰老相关信号转导网络的调控，与肿瘤、心血管疾病和衰老的发生、发展密切相关。本文对miR-34家族在上述领域中的功能研究进行综述。

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	陈晨
	王欣
	沈兴家

关键词 ： microRNA, miR-34, 肿瘤, 心血管疾病, 衰老, 综述文献

收稿日期: 2015-03-26

基金资助:国家自然科学基金资助项目（31172266）；江苏省研究生培养创新工程项目（CXZZ12-0726）。

通讯作者: 沈兴家，研究员，博士生导师，Email：shenxjsri@ 163.com。

作者简介: 陈晨（1988-），女，云南昆明人，硕士生。

链接本文:

https://xb.wmu.edu.cn/CN/ 或 https://xb.wmu.edu.cn/CN/Y2016/V46/I3/231

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