Application of phloroglucinol in the treatment of acute biliary colic
LI Ying1, YU Fuxiang2, YE Yuanyuan1, LIN Weihong1, ZHANG Ruodan1, SUN Hongwei2.
1.Department of Operating Room, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015; 2.Department of Hepatobiliary Surgery, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015
LI Ying,YU Fuxiang,YE Yuanyuan, et al. Application of phloroglucinol in the treatment of acute biliary colic[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(3): 220-222.
Abstract:Objective: To analyze the value of phloroglucinol in the treatment of acute biliary colic. Methods: Three hundred and sixty-eight patients with acute biliary colic were randomly divided into two groups, 236 as the treatment group and 132 as the control group. 120 mg phloroglucinol was added in 5% glucose solution through intravenous drip in the treatment group, while 10 mg anisodamine through the same way in the control. Both two groups used associated antibiotics. The anticolic efficacy was analyzed as well as the side effects. Results: One hour after treatment, the excellence rate of the treatment group was 69.1%, while total efficacy rate was 91.1% and the excellence rate of the control group was 53.0%, while total efficacy rate was 74.2%. There was significant difference between the treatment group and the control group (P<0.05). The incidence rate of the side effects in the treatment group was 0.9%, while 95.4% in the control. There was significant difference between these two groups (P<0.05). Conclusion: As phloroglucinol has better curative effect and fewer side effects in the treatment of acute biliary colic, it is worth of promotion and utilization in the clinical medical treatment.