WU Qing,CHEN Lijiang,XU Chunquan, et al. Distribution and drug resistance of pathogenic bacteria isolated from blood culture in outpatients[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(3): 211-214.
Abstract：Objective: To investigate distribution and drug resistance of pathogenic bacteria isolated from blood culture in outpatients, to provide reference for the clinical rational use of antibiotics. Methods: Blood samples were cultured by BacT/Alert 3D automated system, the identification of strains and the drug susceptibility testing were performed by VITEK 2 COMPACT system, the data were analyzed with Whonet 5.6 software. Results: Totally 1 221 strains were isolated from 7 774 blood culture specimens in outpatients, with the positive rate of 15.7%, there were 569 positive cultures after the repeated strains were get rid of. Among the bacterial strains ,the percentages of the gram-negative bacteria, gram-positive bacteria and fungi were 57.1% (325 strains), 41.7% (237 strains) and 1.2% (7 strains), respectively. Pathogenic bacteria resistance rate was relatively low, the positive rate of ESBLs in Klebsiella pneumoniae was 11.1%, resistance of methicillin-resistant Staphylococcus aureus isolation rate was 28.6%; separation of Enterobacteriaceae to carbapenem antibacterial drug resistance<1.0%, vancomycin resistant Staphylococcus aureus did not be found. Conclusion: The main pathogens of outpatient blood culture are Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae, and these bacteria are better sensitivity to commonly used antibiotics in clinical practice.
